Coumarin-based near-infrared fluorogenic probes: Recent advances, challenges and future perspectives

Y Fan, Y Wu, J Hou, P Wang, X Peng, G Ge - Coordination Chemistry …, 2023 - Elsevier
Coumarin-based fluorogenic probes have emerged as preferred imaging tools to real-time
and non-invasively monitor target analyte (s) in biological systems, due to their inherent …

Organelle-targeting ratiometric fluorescent probes: design principles, detection mechanisms, bio-applications, and challenges

MK Goshisht, N Tripathi, GK Patra, M Chaskar - Chemical Science, 2023 - pubs.rsc.org
Biological species, including reactive oxygen species (ROS), reactive sulfur species (RSS),
reactive nitrogen species (RNS), F−, Pd2+, Cu2+, Hg2+, and others, are crucial for the …

Ratiometric fluorescent probes for pH mapping in cellular organelles

S Munan, R Yadav, N Pareek, A Samanta - Analyst, 2023 - pubs.rsc.org
The intracellular pH (pHi) in organelles, including mitochondria, endoplasmic reticulum,
lysosomes, and nuclei, differs from the cytoplasmic pH, and thus maintaining the pH of these …

Fluorescent probes for targeting endoplasmic reticulum: design strategies and their applications

D Singh, D Rajput, S Kanvah - Chemical Communications, 2022 - pubs.rsc.org
Advances in developing organic fluorescent probes and fluorescence imaging techniques
have enhanced our understanding of cell biology. The endoplasmic reticulum (ER) is a …

Single fluorescent probes enabling simultaneous visualization of duple organelles: Design principles, mechanisms, and applications

M Tian, J Zhan, W Lin - Coordination Chemistry Reviews, 2022 - Elsevier
A unique kind of fluorescent probes which can target duple organelles have been
continuously presented in very recent years. These probes have demonstrated great …

Recent progress on NIR fluorescent probes for enzymes

J Zhao, T Ma, B Chang, J Fang - Molecules, 2022 - mdpi.com
The majority of diseases' biomarkers are enzymes, and the regulation of enzymes is
fundamental but crucial. Biological system disorders and diseases can result from abnormal …

Precise subcellular targeting approaches for organelle-related disorders

G Shim, YS Youn - Advanced Drug Delivery Reviews, 2024 - Elsevier
Pharmacological research has expanded to the nanoscale level with advanced imaging
technologies, enabling the analysis of drug distribution at the cellular organelle level. These …

Activity-based sensing for chemistry-enabled biology: illuminating principles, probes, and prospects for boronate reagents for studying hydrogen peroxide

MS Messina, G Quargnali, CJ Chang - ACS bio & med chem Au, 2022 - ACS Publications
Activity-based sensing (ABS) offers a general approach that exploits chemical reactivity as a
method for selective detection and manipulation of biological analytes. Here, we illustrate …

Lysosome-targeting luminescent lanthanide complexes: from molecular design to bioimaging

DB Ambiliraj, B Francis, MLP Reddy - Dalton Transactions, 2022 - pubs.rsc.org
Lysosomes are essential acidic cytoplasmic membrane-bound organelles in human cells
that play a critical role in many cellular events. A comprehensive understanding of lysosome …

A dual-targeting fluorescent probe for simultaneous and discriminative visualization of lipid droplets and endoplasmic reticulum

F Meng, J He, J Niu, Y Li, P Gao, X Yu - Journal of Materials Chemistry …, 2022 - pubs.rsc.org
A single fluorescent probe (SF-probe) that can simultaneously and discriminatively visualize
two organelles is a powerful tool to investigate their interaction in cellular processes …