Multiscale modeling of blood flow: from single cells to blood rheology
Mesoscale simulations of blood flow, where the red blood cells are described as deformable
closed shells with a membrane characterized by bending rigidity and stretching elasticity …
closed shells with a membrane characterized by bending rigidity and stretching elasticity …
Hydrodynamics in cell studies
D Huber, A Oskooei, X Casadevall i Solvas… - Chemical …, 2018 - ACS Publications
Hydrodynamic phenomena are ubiquitous in living organisms and can be used to
manipulate cells or emulate physiological microenvironments experienced in vivo …
manipulate cells or emulate physiological microenvironments experienced in vivo …
Red blood cell shape transitions and dynamics in time-dependent capillary flows
SM Recktenwald, K Graessel, FM Maurer, T John… - Biophysical …, 2022 - cell.com
The dynamics of single red blood cells (RBCs) determine microvascular blood flow by
adapting their shape to the flow conditions in the narrow vessels. In this study, we explore …
adapting their shape to the flow conditions in the narrow vessels. In this study, we explore …
Numerical–experimental observation of shape bistability of red blood cells flowing in a microchannel
Red blood cells flowing through capillaries assume a wide variety of different shapes owing
to their high deformability. Predicting the realized shapes is a complex field as they are …
to their high deformability. Predicting the realized shapes is a complex field as they are …
Fluid vesicles in flow
We review the dynamical behavior of giant fluid vesicles in various types of external
hydrodynamic flow. The interplay between stresses arising from membrane elasticity …
hydrodynamic flow. The interplay between stresses arising from membrane elasticity …
Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones
Hemostasis is a complex physiological mechanism that functions to maintain vascular
integrity under any conditions. Its primary components are blood platelets and a coagulation …
integrity under any conditions. Its primary components are blood platelets and a coagulation …
Deformation of spherical compound capsules in simple shear flow
The deformation of a compound capsule (an elastic capsule with a smaller capsule inside)
in simple shear flow is studied by using three-dimensional numerical simulations based on a …
in simple shear flow is studied by using three-dimensional numerical simulations based on a …
Microfluidics approach to the mechanical properties of red blood cell membrane and their effect on blood rheology
C Trejo-Soto, GR Lázaro, I Pagonabarraga… - Membranes, 2022 - mdpi.com
In this article, we describe the general features of red blood cell membranes and their effect
on blood flow and blood rheology. We first present a basic description of membranes and …
on blood flow and blood rheology. We first present a basic description of membranes and …
Effect of cell age and membrane rigidity on red blood cell shape in capillary flow
Blood flow in the microcirculatory system is crucially affected by intrinsic red blood cell
(RBC) properties, such as their deformability. In the smallest vessels of this network, RBCs …
(RBC) properties, such as their deformability. In the smallest vessels of this network, RBCs …
Numerical simulations of complex fluid-fluid interface dynamics
Interfaces between two fluids are ubiquitous and of special importance for industrial
applications, eg, stabilisation of emulsions. The dynamics of fluid-fluid interfaces is difficult to …
applications, eg, stabilisation of emulsions. The dynamics of fluid-fluid interfaces is difficult to …