Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules
M Lang, A Carvalho, Z Baharoglu… - … and Molecular Biology …, 2023 - Am Soc Microbiol
Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …
pathogens. While their use declined with the discovery of new antibiotics, they are now …
RavA‐ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in Vibrio cholerae
E Krin, A Carvalho, M Lang, A Babosan… - Microbiology …, 2023 - Am Soc Microbiol
RavA-ViaA were reported to play a role in aminoglycoside (AG) sensitivity, but the
mechanisms remain elusive. Here, we performed competition and survival experiments to …
mechanisms remain elusive. Here, we performed competition and survival experiments to …
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
M Lang, S Renard, I El-Meouche, A Amoura… - bioRxiv, 2023 - biorxiv.org
Aminoglycosides (AGs) are broad-spectrum antibiotics effective against Gram-negative
bacteria. AG uptake depends on membrane potential, but the precise mechanisms are …
bacteria. AG uptake depends on membrane potential, but the precise mechanisms are …