Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic that has infected over a hundred million people globally. There have been …

Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …

Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell
membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like …

Positive strand RNA viruses replicate in the cytoplasm of infected cells and induce
intracellular membranous compartments harboring the sites of viral RNA synthesis. These …

Replication of positive-strand RNA viruses occurs in tight association with reorganized host
cell membranes. In a concerted fashion, viral and cellular factors generate distinct organelle …

Viruses subvert the functions of their host cells to replicate and form new viral progeny. The
endoplasmic reticulum (ER) has been identified as a central organelle that governs the …

Hepatitis C Virus (HCV) infects over 150 million people worldwide. In most cases HCV
infection becomes chronic, causing liver disease ranging from fibrosis to cirrhosis and …

Acyl-CoA: glycerol-3-phosphate acyltransferase (GPAT) and acyl-CoA: 1-acyl-glycerol-3-
phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol …

To cause infection, a virus enters a host cell, replicates, and assembles, with the resulting
new viral progeny typically released into the extracellular environment to initiate a new …