Cardiovascular diseases (CVDs) comprise a group of disorders ranging from peripheral
artery, coronary artery, cardiac valve, cardiac muscle, and congenital heart diseases to …

Current methods to differentiate cardiomyocytes from human pluripotent stem cells (PSCs)
inadequately recapitulate complete development and result in PSC-derived cardiomyocytes …

MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …

Cardiovascular diseases (CVDs) encompass a range of disorders, from congenital heart
malformation, cardiac valve, peripheral artery, coronary artery, cardiac muscle diseases, and …

MicroRNAs (miRNAs) are a class of non-coding RNAs of about 20 nucleotides in length,
involved in the regulation of many biochemical pathways in the human body. The level of …

Cardiovascular disease is a leading cause of disability and death worldwide. Although the
survival rate of patients with heart diseases can be improved with contemporary …

Ischaemia-reperfusion injury (IRI) is closely related to cardiovascular disease (CVD), which
is the leading cause of death and disability. Exosomes appear to be involved in several …

Human-induced pluripotent stem cells (hiPSCs) are discussed as disease modeling for
optimization and adaptation of therapy to each individual. However, the fundamental …

Key Points• Why do we need biomimicry? Which challenges does it aim to overcome?•
Systemic delivery of free drugs has limitations. These limitations include rapid systemic …

Background As the fetal heart develops, cardiomyocyte proliferation potential decreases
while fatty acid oxidative capacity increases in a highly regulated transition known as …