[HTML][HTML] Gastric cancer treatment: recent progress and future perspectives

WL Guan, Y He, RH Xu - Journal of hematology & oncology, 2023 - Springer
Gastric cancer (GC) is one of the most common malignancies worldwide. Most patients are
diagnosed at advanced stages due to the subtle symptoms of earlier disease and the low …

Current developments in gastric cancer: from molecular profiling to treatment strategy

M Alsina, V Arrazubi, M Diez, J Tabernero - … Reviews Gastroenterology & …, 2023 - nature.com
Gastric cancer and gastro-oesophageal junction cancer represent a global health-care
challenge. Despite the efficacy of improved chemotherapy and surgical options, these …

Current treatment and recent progress in gastric cancer

SS Joshi, BD Badgwell - CA: a cancer journal for clinicians, 2021 - Wiley Online Library
Gastric cancer is not a top‐10 malignancy in the United States but represents one of the
most common causes of cancer death worldwide. Biological differences between tumors …

Trastuzumab deruxtecan in previously treated HER2-positive gastric cancer

K Shitara, YJ Bang, S Iwasa, N Sugimoto… - … England Journal of …, 2020 - Mass Medical Soc
Abstract Background Trastuzumab deruxtecan (DS-8201) is an antibody-drug conjugate
consisting of an anti-HER2 (human epidermal growth factor receptor 2) antibody, a …

HER2-targeted therapies—a role beyond breast cancer

DY Oh, YJ Bang - Nature reviews Clinical oncology, 2020 - nature.com
HER2 is an established therapeutic target in a large subset of women with breast cancer; a
variety of agents including trastuzumab, pertuzumab, lapatinib, neratinib and trastuzumab …

The Chinese Society of Clinical Oncology (CSCO): clinical guidelines for the diagnosis and treatment of gastric cancer, 2021

FH Wang, XT Zhang, YF Li, L Tang, XJ Qu… - Cancer …, 2021 - Wiley Online Library
There exist differences in the epidemiological characteristics, clinicopathological features,
tumor biological characteristics, treatment patterns, and drug selections between gastric …

Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm

Y Nakamura, A Kawazoe, F Lordick… - Nature reviews Clinical …, 2021 - nature.com
Advances in cancer biology and sequencing technology have enabled the selection of
targeted and more effective treatments for individual patients with various types of solid …

Targeted therapies in advanced gastric cancer

TH Patel, M Cecchini - Current Treatment Options in Oncology, 2020 - Springer
Opinion statement Despite a decreasing incidence in the USA, gastric cancer is highly
prevalent worldwide. Furthermore, gastric cancer remains highly lethal with median survival …

Gastric cancer

E Van Cutsem, X Sagaert, B Topal, K Haustermans… - The Lancet, 2016 - thelancet.com
Gastric cancer is one of the leading causes of cancer-related death worldwide. Many
patients have inoperable disease at diagnosis or have recurrent disease after resection with …

Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or …

Z Peng, T Liu, J Wei, A Wang, Y He… - Cancer …, 2021 - Wiley Online Library
Background Current treatment options for human epidermal growth factor receptor 2 (HER2)‐
overexpressing gastric cancer at third‐line have shown limited clinical benefit. Further, there …