• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Hypertensive disorders of pregnancy (HDP) remain one of the major causes of pregnancy-
related maternal and fetal morbidity and mortality worldwide. Affected women are also at …

This statement summarizes evidence that adverse pregnancy outcomes (APOs) such as
hypertensive disorders of pregnancy, preterm delivery, gestational diabetes, small-for …

Beyond conventional risk factors for cardiovascular disease, women face an additional
burden of sex-specific risk factors. Key stages of a woman's reproductive history may …

Preeclampsia (PE) is a multisystem disorder that typically affects 2%− 5% of pregnant
women and is one of the leading causes of maternal and perinatal morbidity and mortality …

Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Alzheimer disease (AD) is characterized by wide heterogeneity in cognitive and behavioural
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …

Two important maternal cardiometabolic disorders (CMDs), hypertensive disorders in
pregnancy (HDP)(including pre-eclampsia) and gestational diabetes mellitus (GDM), result …

Background: Women with a history of certain pregnancy complications are at higher risk for
cardiovascular (CVD) disease. However, most clinical guidelines only recommend …

Background—Preeclampsia is a pregnancy-specific disorder resulting in hypertension and
multiorgan dysfunction. There is growing evidence that these effects persist after pregnancy …