Elucidating of Fluconazole Cocrystallization With a Cutting-Edge Nutraceutical Coformer for Enhanced Formulation Strategies

P Vithlapara, M Chotaliya, D Mori, K Dudhat - Journal of Pharmaceutical …, 2024 - Springer
Introduction This current research reports the synthesis and characterization of a cocrystal of
Fluconazole (FLU), a widely used antifungal drug, with a nutraceutical coformer (NCF) that …

Advances in Carbamazepine Cocrystals: A Review

SS Kalantri, MD Yadav - Crystal Research and Technology, 2024 - Wiley Online Library
Carbamazepine (CBZ), a widely used antiepileptic drug, is known for its therapeutic efficacy
but exhibits suboptimal physicochemical characteristics, including limited bioavailability, low …

Rational Design of the Carbamazepine Ternary Cocrystals

DE Boycov, KV Drozd, AN Manin… - Crystal Growth & …, 2024 - ACS Publications
The first ternary cocrystals of carbamazepine (CBZ) were successfully identified through a
large-scale screening. A design strategy involved the use of an aliphatic dicarboxylic acid to …

Drug–Drug Cocrystal Alloy and Nanoformulation of Cytarabine: Optimized Biopharmaceutical Property and Synergistic Antitumor Efficacy

YM Yu, XJ Li, FZ Bu, ZL Zhao, ZY Wu… - Molecular …, 2024 - ACS Publications
An integrated strategy by combining cocrystallization with nanotechnology is developed to
optimize in vitro/vivo performances of marine antitumor drug cytarabine (ARA) and further …

What Has Carbamazepine Taught Crystal Engineers?

AV Hall, AJ Cruz-Cabeza, JW Steed - Crystal Growth & Design, 2024 - ACS Publications
The antiepilepsy drug carbamazepine is one of the most studied pharmaceuticals in the
world. The rich story of its solid forms, cocrystals, and formulation is a microcosm of the …

Two novel drug-nutraceutical cocrystal hydrates of carbamazepine: The influence of isomerism in trihydroxybenzoic acids on the in vitro/in vivo properties

DE Boycov, KV Drozd, AN Manin, AV Churakov… - Journal of Molecular …, 2024 - Elsevier
Two novel drug-nutraceutical cocrystal hydrates based on the antiepileptic carbamazepine
(CBZ) with isomeric trihydroxybenzoic acids, including 3, 4, 5-trihydroxybenzoic acid …

Tuning of a Hydrogen‐Bonded Organic Framework by Liquid‐Assisted Mechanosynthesis between trans‐Aconitic Acid and Isonicotinamide

R Thakuria, D Gogoi, T Sasaki, N Kalita… - … A European Journal, 2024 - Wiley Online Library
Cocrystallization of trans‐aconitic acid (TACA) and isonicotinamide (INA) using liquid
assisted mechanochemical grinding results in a unique supramolecular hydrogen‐bonded …