Third-line antiretroviral therapy program in the South African public sector: cohort description and virological outcomes

M Moorhouse, G Maartens, WDF Venter… - JAIDS Journal of …, 2019 - journals.lww.com
Background: The World Health Organization recommends that antiretroviral therapy (ART)
programs in resource-limited settings develop third-line ART policies. South Africa …

Virological outcomes of third-line antiretroviral therapy in a global context: a systematic reviews and meta-analysis

TA Kitaw, BB Abate, G Yilak, BD Tilahun… - AIDS Research and …, 2024 - Springer
Background Despite remarkable progress, HIV's influence on global health remains firm,
demanding continued attention. Understanding the effectiveness of third-line antiretroviral …

HIV-1 Protease as DNA Immunogen against Drug Resistance in HIV-1 Infection: DNA Immunization with Drug Resistant HIV-1 Protease Protects Mice from Challenge …

S Petkov, A Kilpeläinen, E Bayurova, A Latanova… - Cancers, 2022 - mdpi.com
Simple Summary DNA immunization with drug-resistant HIV-1 protease (DR PR) is
proposed as immunotherapy to prevent the evolution of HIV-1 towards drug resistance and …

Predictors of switch to and early outcomes on third-line antiretroviral therapy at a large public-sector clinic in Johannesburg, South Africa

D Evans, K Hirasen, R Berhanu, G Malete, P Ive… - AIDS Research and …, 2018 - Springer
Background While efficacy data exist, there are limited data on the outcomes of patients on
third-line antiretroviral therapy (ART) in sub-Saharan Africa in actual practice. Being able to …

HIV-1 acquired drug resistance to integrase inhibitors in a cohort of antiretroviral therapy multi-experienced Mexican patients failing to raltegravir: a cross-sectional …

A Orta-Resendiz, RA Rodriguez-Diaz… - AIDS research and …, 2020 - Springer
Background In resource-limited settings, multi-experienced HIV infected patients are often
prescribed raltegravir for salvage therapy. Patients failing raltegravir-containing regimens …

Prevalence, rate, and predictors of virologic failure among adult HIV-Infected clients on second-line antiretroviral therapy (ART) in Tanzania (2018–2020): a …

ET Mwavika, PP Kunambi, SJ Masasi, N Lema… - Bulletin of the National …, 2024 - Springer
Background Antiretroviral therapy (ART) has been proven to be highly effective in reducing
the impact of human immunodeficiency virus (HIV) infection. However, as more people …

Predictors of failure on second-line antiretroviral therapy with protease inhibitor mutations in Uganda

H Musana, JT Ssensamba, M Nakafeero… - AIDS Research and …, 2021 - Springer
Introduction Failure on second-line antiretroviral therapy (ART) with protease inhibitor (PI)
mutations (VF-M) is on the rise. However, there is a paucity of information on the factors …

Treatment outcomes of third-line antiretroviral regimens in HIV-infected THAI adolescents

W Prasitsuebsai, J Sophonphan… - The Pediatric …, 2017 - journals.lww.com
Background: Efficacy and safety data of third-line antiretroviral (ARV) regimens in
adolescents are limited. Methodology: This study enrolled HIV-infected Thais who were …

Health outcomes among HIVpositive Latinos initiating antiretroviral therapy in North America versus Central and South America

C Cesar, JR Koethe, MJ Giganti… - Journal of the …, 2016 - Wiley Online Library
Introduction Latinos living with HIV in the Americas share a common ethnic and cultural
heritage. In North America, Latinos have a relatively high rate of new HIV infections but …

Durability of efavirenz compared with boosted protease inhibitor-based regimens in antiretroviral-naïve patients in the Caribbean and Central and South America

Y Caro-Vega, PF Belaunzarán-Zamudio… - Open Forum …, 2018 - academic.oup.com
Background Efavirenz (EFV) and boosted protease inhibitors (bPIs) are still the preferred
options for firstline antiretroviral regimens (firstline ART) in Latin America and have …