Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

3D cell culture systems: tumor application, advantages, and disadvantages

O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Towards organoid culture without Matrigel

MT Kozlowski, CJ Crook, HT Ku - Communications biology, 2021 - nature.com
Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

Reversed-engineered human alveolar lung-on-a-chip model

D Huang, T Liu, J Liao, S Maharjan… - Proceedings of the …, 2021 - National Acad Sciences
Here, we present a physiologically relevant model of the human pulmonary alveoli. This
alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Sprayable hydrogel dressing accelerates wound healing with combined reactive oxygen species-scavenging and antibacterial abilities

H Cheng, Z Shi, K Yue, X Huang, Y Xu, C Gao, Z Yao… - Acta biomaterialia, 2021 - Elsevier
Wound management poses a considerable economic burden on the global healthcare
system, considering the impacts of wound infection, delayed healing and scar formation. To …

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Bioprinting: From Tissue and Organ Development to in Vitro Models

C Mota, S Camarero-Espinosa, MB Baker… - Chemical …, 2020 - ACS Publications
Bioprinting techniques have been flourishing in the field of biofabrication with pronounced
and exponential developments in the past years. Novel biomaterial inks used for the …