Caveolae are a highly abundant but enigmatic feature of mammalian cells. They form
remarkably stable membrane domains at the plasma membrane but can also function as …

Congenital generalized lipodystrophy (CGL) is a heterogeneous autosomal recessive
disorder characterized by a near complete lack of adipose tissue from birth and, later in life …

The functions of caveolae, the characteristic plasma membrane invaginations, remain
debated. Their abundance in cells experiencing mechanical stress led us to investigate their …

While severe acute respiratory syndrome coronavirus (SARS-CoV) was initially thought to
enter cells through direct fusion with the plasma membrane, more recent evidence suggests …

Receptor endocytosis is a fundamental step in controlling the magnitude, duration, and
nature of cell signaling events. Confluent endothelial cells are contact inhibited in their …

Cellular organelles have characteristic morphologies that arise as a result of different local
membrane curvatures. A striking example is the endoplasmic reticulum (ER), which consists …

This paper presents a review of imaging techniques and of their utility in system biology.
During the last decade systems biology has matured into a distinct field and imaging has …

Membranes of intracellular organelles are characterized by large curvatures with radii of the
order of 10–30 nm. While, generally, membrane curvature can be a consequence of any …

The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that
consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The …

Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma
membrane. They are involved in cell signalling and transport and have been shown critically …