Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Biofilm of Candida albicans: formation, regulation and resistance

R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

Cryptococcal meningitis

L Tugume, K Ssebambulidde, J Kasibante… - Nature Reviews …, 2023 - nature.com
Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Candidiasis and Mechanisms of Antifungal Resistance

S Bhattacharya, S Sae-Tia, BC Fries - Antibiotics, 2020 - mdpi.com
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

Cryptococcus neoformans, a global threat to human health

Y Zhao, L Ye, F Zhao, L Zhang, Z Lu, T Chu… - Infectious Diseases of …, 2023 - mednexus.org
Background Emerging fungal pathogens pose important threats to global public health. The
World Health Organization has responded to the rising threat of traditionally neglected …

Clinical practice guideline for the management of candidiasis: 2016 update by the Infectious Diseases Society of America

PG Pappas, CA Kauffman, DR Andes… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Antifungal drugs

J Houšť, J Spížek, V Havlíček - Metabolites, 2020 - mdpi.com
We reviewed the licensed antifungal drugs and summarized their mechanisms of action,
pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1 …

Pharmacokinetics of antifungal drugs: practical implications for optimized treatment of patients

R Bellmann, P Smuszkiewicz - Infection, 2017 - Springer
Introduction Because of the high mortality of invasive fungal infections (IFIs), appropriate
exposure to antifungals appears to be crucial for therapeutic efficacy and safety. Materials …

Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

Antifungal agents: spectrum of activity, pharmacology, and clinical indications

JE Nett, DR Andes - Infectious Disease Clinics, 2016 - id.theclinics.com
Continued advancement of medical science offers life-saving treatment options for a variety
of hematologic, oncologic, and rheumatologic conditions. Immunosuppression, a common …