Purpose We set out to summarize the current knowledge on vasoactive drugs and their use
in the management of shock to inform physicians' practices. Methods This is a narrative …

After fluid administration for vasodilatory shock, vasopressors are commonly infused.
Causes of vasodilatory shock include septic shock, post-cardiovascular surgery, post-acute …

Purpose Delays in achieving target mean arterial pressure (MAP) are associated with
increased morbidity and mortality in patients with septic shock. This trial was conducted to …

Background Vasopressin (AVP) is commonly added to norepinephrine (NE) to reverse
shock in patients with sepsis. However, there are no data to support the appropriate strategy …

This review of the use of vasopressin aims to be comprehensive and highly practical, based
on the available scientific evidence and our extensive clinical experience with the drug. It …

Objectives: Use of calcium channel blockers has been found to improve sepsis outcomes in
animal studies and one clinical study. This study determines whether the use of calcium …

Background: There is little data guiding clinicians on how to discontinue vasopressors
among septic shock patients on concomitant norepinephrine (NE) and vasopressin (VP) …

Septic shock is defined by the need for vasopressor agents to correct hypotension and lactic
acidosis resulting from infection, with 30%-40% case fatality rates. The care of patients with …

Study Objectives Patients with septic shock often require vasoactive agents for
hemodynamic support; however, the optimal approach to discontinuing these agents once …

Purpose: To evaluate the effects of midodrine in addition to intravenous vasopressor therapy
on outcomes in adults recovering from shock. Materials and Methods: PubMed, Scopus …