Unraveling the epigenetic fabric of type 2 diabetes mellitus: pathogenic mechanisms and therapeutic implications

C Jazieh, TZ Arabi, Z Asim, BN Sabbah… - Frontiers in …, 2024 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a rapidly escalating global health concern, with its
prevalence projected to increase significantly in the near future. This review delves into the …

Applicability of mesenchymal stem cell-derived exosomes as a cell-free miRNA therapy and epigenetic modifiers for diabetes

S Sharma, R Bhonde - Epigenomics, 2023 - Taylor & Francis
Given that exosome nanovesicles constitute various growth factors, miRNAs and lncRNAs,
they have implications for epigenetic modifications. Few studies have shown that exosomes …

Integrative Metabolomic Analysis of Serum and Selected Serum Exosomal microRNA in Metastatic Castration-Resistant Prostate Cancer

D Evin, A Evinová, E Baranovičová… - International Journal of …, 2024 - mdpi.com
Metastatic castration-resistant prostate cancer (mCRPC) remains a lethal disease due to the
absence of effective therapies. A more comprehensive understanding of molecular events …

[HTML][HTML] Research on Traditional Chinese Medicine Syndrome Animal Models and Multi-omics Biomarkers in Type II Diabetes: A Review

Y Wang, Y Gao, B Zhao - Pharmacological Research-Modern Chinese …, 2024 - Elsevier
Introduction Diabetes, a chronic metabolic disease marked by hyperglycemia,
predominantly manifests as Type 2 Diabetes Mellitus (T2DM), representing over 90% of …

Predictive value of circulating miR-409-3p for major adverse cardiovascular events in patients with type 2 diabetes mellitus and coronary heart disease

L Cao, X Pan, Y Li, W Jia, J Huang, J Liu - Endocrinología, Diabetes y …, 2024 - Elsevier
Objectives To investigate the serum levels of miR-409-3p in patients with type 2 diabetes
mellitus (T2DM) complicated with coronary heart disease (CHD) and its effect on high …

Circulating miRNAs As Biomarkers for Early Disease Diagnosis

J Holdmann, A Savelsbergh, L Markert - miRNAs, Human Health and Diseases - Springer
In today's medical world, early detection of disease is a crucial factor in ensuring that
patients receive appropriate and adequate treatment. Particularly in the context of cancer …