Although cancer was originally considered a disease driven only by genetic mutations, it has
now been proven that it is also an epigenetic disease driven by DNA hypermethylation …

Aging, which is accompanied by decreased organ function and increased disease
incidence, limits human lifespan and has attracted investigators for thousands of years. In …

Our study aimed to investigate the expression, functional significance, and related
mechanism of long noncoding RNA CRNDE (colorectal neoplasia differentially expressed) …

Cancer is a complex disease in which several molecular and cellular pathways converge to
foster the tumoral phenotype. Notably, in the latest iteration of the cancer hallmarks,“ …

Opioid exposure is known to cause transcriptomic changes in the nucleus accumbens
(NAc). However, no studies to date have investigated cell type-specific transcriptomic …

An increasing number of studies have clarified the functional roles of RNA-binding proteins
(RBPs) in driving post-transcriptional mechanisms of cancer progression. In this study, we …

Background Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults. Many previous studies have demonstrated that the infiltrating of immune and stromal …

Post-transcriptional modifications to coding and non-coding RNAs are unquestionably a
pivotal way in which human mRNA and protein diversity can influence the different phases …

Simple Summary Epigenetics studies the alteration of gene expression without changing
DNA sequence and very often, epigenetic dysregulation causes cancer. Alternative splicing …

Eukaryotic gene expression is intricately regulated at multiple levels. The protein‐coding
genes are first transcribed as pre‐mRNAs in the nucleus and undergo a series of RNA …