This review of the familial tumor syndromes involving the endocrine organs is focused on
discussing the main updates on the upcoming fifth edition of the WHO Classification of …

Thyroid carcinomas (TC) are rare in the pediatric population; however, they constitute the
most common endocrine malignancy. Despite some similarities with adult carcinomas, they …

Aims DICER1 germline mutations cause DICER1 syndrome, in which multinodular goitre is
a common feature. Recently, somatic DICER1 mutations have been reported in sporadic …

Purpose: DICER1-related tumor predisposition increases risk for a spectrum of benign and
malignant tumors. In 2018, the International Pleuropulmonary Blastoma (PPB)/DICER1 …

Background Thyroid nodules are commonly faced by clinicians as palpable nodules or
incidentally identified on imaging. Nodules that are found to be suspicious by imaging can …

DGCR8 emerged recently as miRNAs biogenesis pathway protein with a highlighted role in
thyroid disease. This study aimed to characterize this miRNA biogenesis component, in …

Thyroid cancer is the most frequent endocrine malignancy with the majority of cases derived
from thyroid follicular cells and caused by sporadic mutations. However, when at least two or …

Thyroid cancer is the malignant tumor that is increasing most rapidly in the world, mainly at
the expense of sporadic papillary thyroid carcinoma. The somatic alterations involved in the …

Introduction DICER1 mutated thyroid nodules are commonly seen in pediatric populations
often, as part of DICER1 syndrome. We seek to evaluate DICER1 mutated thyroid nodules in …

MicroRNAs (miRNAs) act as negative regulators for protein-coding gene expression
impacting cell proliferation, differentiation, and survival. These miRNAs are frequently …