Exploring the therapeutic potential of chalcones in oncology: A comprehensive review

CS Yadav, I Azad, AR Khan, N Ahmad… - Current Bioactive …, 2024 - ingentaconnect.com
Chalcone is a bioactive flavonoid found in various plants, such as Angelica archangelica,
Pueraria lobata, and Glycyrrhiza glabra. It has been studied extensively in the field of …

Design, in silico studies and biological evaluation of novel chalcones tethered triazolo[3,4-a]isoquinoline as EGFR inhibitors targeting resistance in non-small cell …

N Abdelaal, MA Ragheb, HM Hassaneen… - Scientific Reports, 2024 - nature.com
A novel series of six [1, 2, 4] triazolo [3, 4-a] isoquinolin-3-yl)-3-(1, 3-diphenyl-1 H-pyrazol-4-
yl) prop-2-en-1-ones (3a–3f) was designed and synthesized. They were characterized …

Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene …

NS Ibrahim, HA Sayed, M Sharaky, HM Diab… - Naunyn-Schmiedeberg's …, 2024 - Springer
Eight Novel chalcones were synthesized and their structures were confirmed by different
spectral tools. All the prepared compounds were subjected to SRB cytotoxic screening …

Regioselective synthesis of fused pyrimidines and quinazolines linked to Phenoxy‐N‐arylacetamide moieties as novel hybrid molecules via Biginelli‐like reaction

AM Abdelmoniem, RE Abdelwahab… - Journal of …, 2023 - Wiley Online Library
A novel series of 6‐acetyl‐[1, 2, 4] triazolo [1, 5‐a] pyrimidines, hexahydro‐[1, 2, 4] triazolo
[5, 1‐b] quinazolines, tetrahydrobenzo [4, 5] imidazo [2, 1‐b] quinazolin‐1‐ones, and 3 …

Novel eco-friendly [1,2,4]triazolo[3,4-a]isoquinoline chalcone derivatives efficiency against fungal deterioration of ancient Egyptian mummy cartonnage, Egypt

NS Geweely, MM Soliman, RA Ali… - Archives of …, 2023 - Springer
Fungal deterioration is one of the major factors that significantly contribute to mummy
cartonnage damage. Isolation and molecular identification of thirteen fungal species …

Novel Bis (2‐cyanoacrylamide) Linked to Sulphamethoxazole: Synthesis, DNA Interaction, Anticancer, ADMET, Molecular Docking, and DFT Studies

MA Ragheb, FG Mohamed, HM Diab… - Chemistry & …, 2024 - Wiley Online Library
In the light of advancement and potential extensive use of medication design and therapy,
new bis (cyanoacrylamides) incorporating sulphamethoxazole derivatives (7 a–7 f) were …