Interfering with interferons: A critical mechanism for critical COVID-19 pneumonia

HC Su, H Jing, Y Zhang… - Annual Review of …, 2023 - annualreviews.org
Infection with SARS-CoV-2 results in clinical outcomes ranging from silent or benign
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Autoantibodies in COVID‐19 correlate with antiviral humoral responses and distinct immune signatures

P Taeschler, C Cervia, Y Zurbuchen, S Hasler, C Pou… - Allergy, 2022 - Wiley Online Library
Background Several autoimmune features occur during coronavirus disease 2019 (COVID‐
19), with possible implications for disease course, immunity, and autoimmune pathology. In …

[HTML][HTML] Microvascular significance of TGF-β axis activation in COVID-19

LM Arguinchona, C Zagona-Prizio, ME Joyce… - Frontiers in …, 2023 - frontiersin.org
As 2023 approaches, the COVID-19 pandemic has killed millions. While vaccines have
been a crucial intervention, only a few effective medications exist for prevention and …

COVID-19 Vasculitis and vasculopathy-Distinct immunopathology emerging from the close juxtaposition of Type II Pneumocytes and Pulmonary Endothelial Cells

S Giryes, NL Bragazzi, C Bridgewood… - Seminars in …, 2022 - Springer
Abstract The SARS-CoV-2 virus ACE-2 receptor utilization for cellular entry and the defined
ACE-2 receptor role in cardiovascular medicine hinted at dysregulated endothelial function …

[HTML][HTML] Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

C Carmona-Rivera, Y Zhang, K Dobbs, TE Markowitz… - JCI insight, 2022 - ncbi.nlm.nih.gov
Dysregulation in neutrophil extracellular trap (NET) formation and degradation may play a
role in the pathogenesis and severity of COVID-19; however, its role in the pediatric …

Molecular evidence for SARS-CoV-2 in samples collected from patients with morbilliform eruptions since late 2019 in Lombardy, northern Italy

A Amendola, M Canuti, S Bianchi, S Kumar… - Environmental …, 2022 - Elsevier
As a reference laboratory for measles and rubella surveillance in Lombardy, we evaluated
the association between SARS-CoV-2 infection and measles-like syndromes, providing …

Lack of association between pandemic chilblains and SARS-CoV-2 infection

JR Gehlhausen, AJ Little, CJ Ko… - Proceedings of the …, 2022 - National Acad Sciences
An increased incidence of chilblains has been observed during the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic and attributed to viral infection. Direct …

[HTML][HTML] Complement-mediated microvascular injury and thrombosis in the pathogenesis of severe COVID-19: A review

P Gianni, M Goldin, S Ngu, S Zafeiropoulos… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) causes acute microvascular thrombosis in
both venous and arterial structures which is highly associated with increased mortality. The …

Cutaneous vasculitis and vasculopathy in the era of COVID-19 pandemic

CA Maronese, E Zelin, G Avallone, C Moltrasio… - Frontiers in …, 2022 - frontiersin.org
Cutaneous vasculitides encompass a heterogeneous group of clinicopathological entities,
which may occur as single-organ vasculitis of the skin or present as skin-limited variant of …