Selecting therapeutic targets in inflammatory bowel disease (STRIDE): determining therapeutic goals for treat-to-target

L Peyrin-Biroulet, W Sandborn, BE Sands… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
program was initiated by the International Organization for the Study of Inflammatory Bowel …

The role of endoscopy in inflammatory bowel disease

AK Shergill, JR Lightdale, DH Bruining… - Gastrointestinal …, 2015 - giejournal.org
This is one of a series of statements discussing the use of GI endoscopy in common clinical
situations. The Standards of Practice Committee of the American Society for Gastrointestinal …

ACG clinical guideline: ulcerative colitis in adults

DT Rubin, AN Ananthakrishnan… - Official journal of the …, 2019 - journals.lww.com
Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the
preferred approach to the management of adults with UC and represent the official practice …

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

Y Haberman, R Karns, PJ Dexheimer… - Nature …, 2019 - nature.com
Molecular mechanisms driving disease course and response to therapy in ulcerative colitis
(UC) are not well understood. Here, we use RNAseq to define pre-treatment rectal gene …

Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification

A Levine, A Griffiths, J Markowitz… - Inflammatory bowel …, 2011 - academic.oup.com
Background Crohn's disease and ulcerative colitis are complex disorders with some shared
and many unique predisposing genes. Accurate phenotype classification is essential in …

Management of paediatric ulcerative colitis, part 2: acute severe colitis—an evidence-based consensus guideline from the European Crohn's and Colitis Organization …

D Turner, FM Ruemmele… - Journal of pediatric …, 2018 - journals.lww.com
Methods: These guidelines are a joint effort of the European Crohn's and Colitis
Organization (ECCO) and the European Society of Paediatric Gastroenterology, Hepatology …

The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease

JD Lewis - Gastroenterology, 2011 - Elsevier
Fecal and serologic biomarkers can be used in the diagnosis and management of
inflammatory bowel disease (IBD). Fecal markers such as calprotectin and lactoferrin have …

Management of pediatric ulcerative colitis: joint ECCO and ESPGHAN evidence-based consensus guidelines

D Turner, A Levine, JC Escher… - Journal of pediatric …, 2012 - journals.lww.com
Methods: A group of 27 experts in pediatric IBD participated in an iterative consensus
process including 2 face-to-face meetings, following an open call to ESPGHAN and ECCO …

Positioning and usefulness of biomarkers in inflammatory bowel disease

T Sakurai, M Saruta - Digestion, 2023 - karger.com
Background: Mucosal healing (MH) was proposed to be an ideal treatment goal for patients
with inflammatory bowel disease (IBD). Instead of endoscopy to confirm MH, biomarkers are …

Current best practice for disease activity assessment in IBD

AJ Walsh, RV Bryant, SPL Travis - Nature reviews Gastroenterology & …, 2016 - nature.com
Therapeutic advances in the management of IBD have led to a paradigm shift in the
assessment of IBD disease activity. Beyond clinical remission, objective assessment of …