The advent of immune checkpoint inhibition (ICI) has transformed the treatment paradigm for
bladder cancer. However, despite the success of ICI in other tumour types, the majority of ICI …

Abstract Purpose Bacille Calmette-Guérin (BCG) is a well-established treatment for
preventing or delaying tumour recurrence following high-grade nonmuscle invasive bladder …

Non-muscle invasive bladder cancer (NMIBC) is a major type of bladder cancer with a high
incidence worldwide, resulting in a great disease burden. Treatment and surveillance are …

Introduction Intravesical gemcitabine and docetaxel (Gem/Doce) has been established as a
safe and efficacious salvage treatment for recurrent NMIBC since 2015. Despite widespread …

CD40 is a central costimulatory receptor implicated in productive antitumor immune
responses across multiple cancers, including bladder cancer. Despite strong preclinical …

Introduction The combination of intravesical gemcitabine (Gem) with docetaxel (Doce) or
with mitomycin C (MMC) has been used in the primary setting as an alternative to Bacillus …

Purpose: Patients with bacillus Calmette-Guérin-unresponsive carcinoma in situ are treated
with radical cystectomy or salvage intravesical chemotherapy. Recently, pembrolizumab …

Cretostimogene grenadenorepvec is a serotype-5 oncolytic adenovirus designed to
selectively replicate in cancer cells with retinoblastoma pathway alterations, previously …

The current landscape of salvage therapies for patients with... : Current Opinion in Urology The
current landscape of salvage therapies for patients with bacillus Calmette-Guérin unresponsive …

Objectives Nadofaragene firadenovec is a gene therapy for bacillus Calmette-Guérin (BCG)–
unresponsive non–muscle-invasive bladder cancer (NMIBC) undergoing Food and Drug …