Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical
presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; …

Effective motor performance is important for surviving and thriving, and skilled movement is
critical in many activities. Much theorizing over the past few decades has focused on how …

Parkinson's disease (PD) is the second most common neurodegenerative disorder which
affects 6.1 million people worldwide. The neuropathological hallmarks include the loss of …

Freezing, which manifests during gait and other movements, is an incapacitating motor
symptom experienced by many patients with Parkinson's disease (PD). In rehabilitation …

Bradykinesia is the most important feature contributing to motor difficulties in Parkinson's
disease (PD). However, the pathophysiology underlying bradykinesia is not fully …

Recognizing and characterizing bradykinesia is a critical issue in movement disorders.
Bradykinesia is the core symptom for the definition of parkinsonism and for the diagnosis of …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by severe motor complications caused by a …

Traditionally, the basal ganglia have been considered the main brain region implicated in
Parkinson's disease. This single area perspective gives a restricted clinical picture and limits …

Many neurophysiological abnormalities have been described in the primary motor cortex of
patients with Parkinson's disease. However, it is unclear whether there is any relationship …

Pain is a common nonmotor symptom in patients with Parkinson disease (PD) but the correct
diagnosis of the respective cause remains difficult because suitable tools are lacking, so far …