Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

D Stolz, T Mkorombindo, DM Schumann, A Agusti… - The Lancet, 2022 - thelancet.com
Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

Electronic cigarettes and health outcomes: umbrella and systematic review of the global evidence

E Banks, A Yazidjoglou, S Brown… - Medical Journal of …, 2023 - Wiley Online Library
Objective To review and synthesise the global evidence regarding the health effects of
electronic cigarettes (e‐cigarettes, vapes). Study design Umbrella review (based on major …

[PDF][PDF] SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract

YJ Hou, K Okuda, CE Edwards, DR Martinez… - Cell, 2020 - cell.com
The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …

Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine

MC Madison, CT Landers, BH Gu… - The Journal of …, 2020 - Am Soc Clin Investig
Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular
recreational tool among adolescents and adults. Although the use of ENDS is often …

What are the respiratory effects of e-cigarettes?

JE Gotts, SE Jordt, R McConnell, R Tarran - bmj, 2019 - bmj.com
Electronic cigarettes (e-cigarettes) are alternative, non-combustible tobacco products that
generate an inhalable aerosol containing nicotine, flavors, propylene glycol, and vegetable …

E-cigarette use and respiratory disorders: an integrative review of converging evidence from epidemiological and laboratory studies

TA Wills, SS Soneji, K Choi, I Jaspers… - European Respiratory …, 2021 - Eur Respiratory Soc
Background Use of electronic cigarettes (e-cigarettes) is prevalent among adolescents and
young adults, but there has been limited knowledge about health consequences in human …

Association of e-cigarette use with respiratory disease among adults: a longitudinal analysis

DN Bhatta, SA Glantz - American journal of preventive medicine, 2020 - Elsevier
Introduction E-cigarettes deliver an aerosol of nicotine by heating a liquid and are promoted
as an alternative to combustible tobacco. This study determines the longitudinal …

Chronic e-cigarette use increases neutrophil elastase and matrix metalloprotease levels in the lung

A Ghosh, RD Coakley, AJ Ghio… - American journal of …, 2019 - atsjournals.org
Rationale: Proteolysis is a key aspect of the lung's innate immune system. Proteases,
including neutrophil elastase and MMPs (matrix metalloproteases), modulate cell signaling …

The evolving landscape of e-cigarettes: a systematic review of recent evidence

J Bozier, EK Chivers, DG Chapman, AN Larcombe… - Chest, 2020 - Elsevier
Smoking continues to be a burden to economies and health-care systems across the world.
One proposed solution to the problem has been e-cigarettes; however, because they are a …

E-cigarettes and cardiopulmonary health: review for clinicians

EW Neczypor, MJ Mears, A Ghosh, MF Sassano… - Circulation, 2022 - Am Heart Assoc
Electronic cigarettes (e-cigarettes) are battery powered electronic nicotine delivery systems
that use a propylene glycol/vegetable glycerin base to deliver vaporized nicotine and …