Sniffing around oxytocin: review and meta-analyses of trials in healthy and clinical groups with implications for pharmacotherapy

MJ Bakermans-Kranenburg… - Translational …, 2013 - nature.com
The popularity of oxytocin (OT) has grown exponentially during the past decade, and so has
the number of OT trials in healthy and clinical groups. We take stock of the evidence from …

[HTML][HTML] The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings

D Cochran, D Fallon, M Hill… - Harvard review of …, 2013 - ncbi.nlm.nih.gov
Oxytocin is a peptide hormone integral in parturition, milk let-down, and maternal behaviors
that has been demonstrated in animal studies to be important in the formation of pair bonds …

Meta-analysis of the effects of intranasal oxytocin on interpretation and expression of emotions

J Leppanen, KW Ng, K Tchanturia… - … & Biobehavioral Reviews, 2017 - Elsevier
Accurate interpretation and appropriate expression of emotions are key aspects of social-
cognition. Several mental disorders are characterised by transdiagnostic difficulties in these …

Neurophysiological effects of acute oxytocin administration: systematic review and meta-analysis of placebo-controlled imaging studies

R Wigton, J Radua, P Allen, B Averbeck… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: Oxytocin (OXT) plays a prominent role in social cognition and may have clinical
applications for disorders such as autism, schizophrenia and social anxiety. The neural …

Oxytocin in schizophrenia: pathophysiology and implications for future treatment

KK Goh, CH Chen, HY Lane - International journal of molecular sciences, 2021 - mdpi.com
Schizophrenia is a form of mental disorder that is behaviorally characterized by abnormal
behavior, such as social function deficits or other behaviors that are disconnected from …

Making room for oxytocin in understanding depression

RJ McQuaid, OA McInnis, A Abizaid… - … & Biobehavioral Reviews, 2014 - Elsevier
Depression is accompanied by an array of neurobiological variations, including altered HPA
axis activity, monoamine, growth factor and inflammatory immune functioning. In addition, a …

Exogenous effects of oxytocin in five psychiatric disorders: a systematic review, meta-analyses and a personalized approach through the lens of the social salience …

L Peled-Avron, A Abu-Akel… - … & Biobehavioral Reviews, 2020 - Elsevier
Oxytocin (OT) has been implicated in various aspects of social behaviors. During the past
decades there has been a surge of interest in the therapeutic potential of OT in psychiatric …

Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders

K Macdonald, D Feifel - Frontiers in neuroscience, 2013 - frontiersin.org
Concerns regarding a drought in psychopharmacology have risen from many quarters. From
one perspective, the wellspring of bedrock medications for anxiety disorders, depression …

Oxytocin in the socioemotional brain: implications for psychiatric disorders

P Kirsch - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
The neuropeptide oxytocin (OXT), highly conserved during evolution, is an important
modulator of social and emotional processes across many species. During the last decade …

Oxytocin and social functioning

C Jones, I Barrera, S Brothers, R Ring… - Dialogues in clinical …, 2017 - Taylor & Francis
Social anxiety is a form of anxiety characterized by continuous fear of one or more social or
performance situations. Although multiple treatment modalities (cognitive behavioral …