Recent advances in intranasal liposomes for drug, gene, and vaccine delivery
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases
Q Huang, Y Chen, W Zhang, X Xia, H Li, M Qin… - Journal of Controlled …, 2024 - Elsevier
Despite the increasing global incidence of brain disorders, achieving sufficient delivery
towards the central nervous system (CNS) remains a formidable challenge in terms of …
towards the central nervous system (CNS) remains a formidable challenge in terms of …
Development of atomoxetine-loaded NLC in situ gel for nose-to-brain delivery: optimization, in vitro, and preclinical evaluation
The present study investigates the brain-targeted efficiency of atomoxetine (AXT)-loaded
nanostructured lipid carrier (NLC)-laden thermosensitive in situ gel after intranasal …
nanostructured lipid carrier (NLC)-laden thermosensitive in situ gel after intranasal …
Design of experiment (DoE) as a quality by design (QbD) tool to optimise formulations of lipid nanoparticles for nose-to-brain drug delivery
AC Correia, JN Moreira, JM Sousa Lobo… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction The nose-to-brain route has been widely investigated to improve drug targeting
to the central nervous system (CNS), where lipid nanoparticles (solid lipid nanoparticles …
to the central nervous system (CNS), where lipid nanoparticles (solid lipid nanoparticles …
N-trimethyl chitosan and tripalmitin loaded solid lipid nanoparticles of tofacitinib citrate: Characterization and in-vivo anti-inflammatory assessment
In recent times, solid lipid nanoparticles (SLNs) have emerged as a promising dosage
innovation. However, the concept remains in its infancy as it relates to organ and site …
innovation. However, the concept remains in its infancy as it relates to organ and site …
Tazarotene-calcipotriol loaded Nanostructured lipid carrier enriched hydrogel: a novel dual drug synergistic approach towards Psoriasis management
S Thakur, MM Anjum, S Jaiswal, AK Gautam… - Journal of Drug Delivery …, 2023 - Elsevier
Psoriasis with unclear etiology and pathogenesis is one of the most prevalent chronic skin
diseases. It involves excessive keratinocytes cells hyperproliferation, abnormal vascular …
diseases. It involves excessive keratinocytes cells hyperproliferation, abnormal vascular …
Niosomes gel of apigenin to improve the topical delivery: development, optimization, ex vivo permeation, antioxidant study, and in vivo evaluation
OA Alsaidan, A Zafar, RH Al-Ruwaili… - Artificial Cells …, 2023 - Taylor & Francis
Niosomes (NS) are the promising and novel carrier of the drug for effective transdermal
delivery. Apigenin (AN) is a natural bioactive compound and has various pharmacological …
delivery. Apigenin (AN) is a natural bioactive compound and has various pharmacological …
Polysaccharide-based platforms for nasal delivery: design, features, and perspectives
E Elmowafy, ME Soliman - Journal of Pharmaceutical Investigation, 2023 - Springer
Background Polysaccharides acceded by the Food and Drug Administration are among the
most exploitable polymers for fabricating nasally applied vehicles containing therapeutically …
most exploitable polymers for fabricating nasally applied vehicles containing therapeutically …
Intranasal delivery of sulpiride nanostructured lipid carrier to central nervous system; in vitro characterization and in vivo study
HM Tawfeek, AI Mekkawy, AAH Abdelatif… - Pharmaceutical …, 2024 - Taylor & Francis
The low and erratic oral absorption of sulpiride (SUL) a dopaminergic receptor antagonist,
and its P-glycoprotein efflux in the gastrointestinal tract restricted its oral route for central …
and its P-glycoprotein efflux in the gastrointestinal tract restricted its oral route for central …
Bergenin nano-lipid carrier to improve the oral delivery: development, optimization, in vitro and in vivo evaluation
A Zafar, M Yasir, DS Panda, L Singh - Journal of Drug Delivery Science and …, 2024 - Elsevier
This study aimed to prepare bergenin (BN) loaded nanostructured lipid carrier (NLC) to
improve oral therapeutic efficacy. The preparation of BNNLC involved the utilization of melt …
improve oral therapeutic efficacy. The preparation of BNNLC involved the utilization of melt …