Iron and iron-related proteins in COVID-19

E Suriawinata, KJ Mehta - Clinical and experimental medicine, 2023 - Springer
COVID-19 can cause detrimental effects on health. Vaccines have helped in reducing
disease severity and transmission but their long-term effects on health and effectiveness …

Immune mechanisms in inflammatory anemia

SP Canny, SL Orozco, NK Thulin… - Annual review of …, 2023 - annualreviews.org
Maintaining the correct number of healthy red blood cells (RBCs) is critical for proper
oxygenation of tissues throughout the body. Therefore, RBC homeostasis is a tightly …

Role of red blood cell distribution width, as a prognostic indicator in COVID‐19: a systematic review and meta‐analysis

S Sarkar, S Kannan, P Khanna… - Reviews in Medical …, 2022 - Wiley Online Library
The red blood cell distribution width (RDW), an indicator of anisocytosis has emerged as a
potential tool for risk stratification of critically ill patients with sepsis. Prognostic predictors are …

Alteration of L-Dopa decarboxylase expression in SARS-CoV-2 infection and its association with the interferon-inducible ACE2 isoform

G Mpekoulis, E Frakolaki, S Taka, A Ioannidis… - PLoS …, 2021 - journals.plos.org
L-Dopa decarboxylase (DDC) is the most significantly co-expressed gene with ACE2, which
encodes for the SARS-CoV-2 receptor a ngiotensin-c onverting e nzyme 2 and the interferon …

SARS-CoV-2 infection dysregulates host iron (Fe)-redox homeostasis (Fe-RH): role of Fe-redox regulators, ferroptosis inhibitors, anticoagulants, and iron-chelators in …

SAG Naidu, RA Clemens, AS Naidu - Journal of dietary …, 2023 - Taylor & Francis
Severe imbalance in iron metabolism among SARS-CoV-2 infected patients is prominent in
every symptomatic (mild, moderate to severe) clinical phase of COVID-19. Phase-I–Hypoxia …

It's in the blood: a review of the hematological system in SARS-CoV-2-associated COVID-19

JV Harte, C Coleman-Vaughan… - Critical Reviews in …, 2023 - Taylor & Francis
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to an unprecedented global healthcare crisis. While SARS-CoV-2-associated COVID-19 …

The relationship between hepcidin-mediated iron dysmetabolism and COVID-19 severity: a meta-analysis

D Peng, Y Gao, L Zhang, Z Liu, H Wang… - Frontiers in public …, 2022 - frontiersin.org
Backgrounds Hepcidin has been identified as a systemic iron-regulatory hormone. Recent
studies have suggested that iron metabolism disorders may be involved in the pathogenesis …

[HTML][HTML] Novel aspects of sepsis pathophysiology: NETs, plasma glycoproteins, endotheliopathy and COVID-19

M Nishibori - Journal of Pharmacological Sciences, 2022 - Elsevier
In 2016, sepsis was newly defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. Sepsis remains one of the crucial medical problems …

Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …

Significance of catecholamine biosynthetic/metabolic pathway in SARS-CoV-2 infection and COVID-19 severity

G Mpekoulis, KI Kalliampakou, RS Milona, D Lagou… - Cells, 2022 - mdpi.com
The SARS-CoV-2 infection was previously associated with the expression of the dopamine
biosynthetic enzyme L-Dopa decarboxylase (DDC). Specifically, a negative correlation was …