Bone fragility in diabetes: novel concepts and clinical implications
Increased fracture risk represents an emerging and severe complication of diabetes. The
resulting prolonged immobility and hospitalisations can lead to substantial morbidity and …
resulting prolonged immobility and hospitalisations can lead to substantial morbidity and …
Mechanisms of diabetes mellitus-induced bone fragility
N Napoli, M Chandran, DD Pierroz… - Nature Reviews …, 2017 - nature.com
The risk of fragility fractures is increased in patients with either type 1 diabetes mellitus
(T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in …
(T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in …
Treatment of diabetes in older adults: an Endocrine Society clinical practice guideline
D LeRoith, GJ Biessels, SS Braithwaite… - The Journal of …, 2019 - academic.oup.com
Objective The objective is to formulate clinical practice guidelines for the treatment of
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …
Systemic complications of acromegaly and the impact of the current treatment landscape: an update
MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …
increased mortality when not adequately treated. Substantial advances in acromegaly …
Diabetes and its effect on bone and fracture healing
H Jiao, E Xiao, DT Graves - Current osteoporosis reports, 2015 - Springer
Diabetes mellitus is a metabolic disorder that increases fracture risk, interferes with bone
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …
Management of endocrine disease: secondary osteoporosis: pathophysiology and management
F Mirza, E Canalis - European journal of endocrinology, 2015 - academic.oup.com
Osteoporosis is a skeletal disorder characterized by decreased mass and compromised
bone strength predisposing to an increased risk of fractures. Although idiopathic …
bone strength predisposing to an increased risk of fractures. Although idiopathic …
Impact of diabetes mellitus on bone health
CE Murray, CM Coleman - International journal of molecular sciences, 2019 - mdpi.com
Long-term exposure to a diabetic environment leads to changes in bone metabolism and
impaired bone micro-architecture through a variety of mechanisms on molecular and …
impaired bone micro-architecture through a variety of mechanisms on molecular and …
The risk of hip and non-vertebral fractures in type 1 and type 2 diabetes: a systematic review and meta-analysis update
Background Diabetes is associated with increased fracture risk but we do not know what
affects this risk. We investigated the risk of hip and non-vertebral fractures in diabetes and …
affects this risk. We investigated the risk of hip and non-vertebral fractures in diabetes and …
Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition
Global energy balance in mammals is controlled by the actions of circulating hormones that
coordinate fuel production and utilization in metabolically active tissues. Bone-derived …
coordinate fuel production and utilization in metabolically active tissues. Bone-derived …
Systematic review of type 1 and type 2 diabetes mellitus and risk of fracture
M Janghorbani, RM Van Dam… - American journal of …, 2007 - academic.oup.com
The authors conducted a systematic review of published data on the association between
diabetes mellitus and fracture. The authors searched MEDLINE through June 2006 and …
diabetes mellitus and fracture. The authors searched MEDLINE through June 2006 and …