Covering: 2000 up to 2018 The cytochromes P450 (P450s) are a superfamily of heme-
containing monooxygenases that perform diverse catalytic roles in many species, including …

Covering: up to 2022 Streptomyces are ubiquitous in terrestrial and marine environments,
where they display a fascinating metabolic diversity. As a result, these bacteria are a prolific …

Genome mining of the deep sea-derived Streptomyces atratus SCSIO ZH16 enabled the
activation of a cyclodepsipeptide gene cluster and isolation of its cinnamic acid-bearing …

Cinnamoyl-containing natural products (CCNPs) are a small class of bacterial metabolites
with notable bioactivities. The biosynthesis of cinnamoyl moiety has been proposed to be …

Abstract Non-Ribosomal Peptide Synthetases (NRPSs) assemble a diverse range of natural
products with important applications in both medicine and agriculture. They consist of …

Atrovimycin (1), a cyclodepsipeptide containing a unique vicinal-hydroxylated cinnamic acyl
chain, was isolated and elucidated from Streptomyces atrovirens LQ13. The biosynthetic …

Systematic inactivation of nonribosomal peptide synthetase (NRPS) domains and
translocation of the thioesterase (TE) domain revealed several unprecedented nonlinear …

Cinnamoyl-containing nonribosomal peptides (CCNPs) are a small group of secondary
metabolites with potent biological activities produced by actinobacteria. Two remarkable …

Cinnamoyl-containing nonribosomal peptides (CCNPs) form a unique family of
actinobacterial secondary metabolites and display various biological activities. A new CCNP …

Cinnamoyl-containing nonribosomal peptides (CCNPs) constitute a unique family of
actinobacterial secondary metabolites that display a broad spectrum of biological activities …