[HTML][HTML] Platelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade

D O'Reilly, CA Murphy, R Drew, A El-Khuffash… - Pediatric …, 2022 - nature.com
Sepsis, a dysregulated host response to infection, has been difficult to accurately define in
children. Despite a higher incidence, especially in neonates, a non-specific clinical …

Sepsis-associated thrombocytopenia

CM Larkin, MJ Santos-Martinez, T Ryan… - Thrombosis …, 2016 - thrombosisresearch.com
Severe sepsis now accounts for one quarter of all admissions to Intensive Care Units (ICUs)
and has an incidence of 60/100,000 in the United Kingdom [1]. Based on recent figures from …

[HTML][HTML] Thrombocytopenia in neonatal sepsis: Incidence, severity and risk factors

IMC Ree, SF Fustolo-Gunnink, V Bekker… - PloS one, 2017 - journals.plos.org
Objectives Thrombocytopenia is a frequent problem in neonatal sepsis and is among the
most predictive, independent risk factors for sepsis-associated mortality. This study aims to …

[HTML][HTML] Time course of immature platelet count and its relation to thrombocytopenia and mortality in patients with sepsis

K Koyama, S Katayama, T Muronoi, K Tonai, Y Goto… - PloS one, 2018 - journals.plos.org
Introduction The pathogenesis of thrombocytopenia in patients with sepsis is not fully
understood. The aims of this study were to investigate changes in thrombopoietic activity …

[HTML][HTML] Sepsis and thrombocytopenia: a nowadays problem

DA Gonzalez, R Kumar, S Asif, A Bali, AK Dang - Cureus, 2022 - ncbi.nlm.nih.gov
Sepsis is a life-threatening organ failure produced by a dysregulated host response to
infection that involves 15.6% of hospital mortality. The most common signs and symptoms of …

Hematologic aspects of early and late-onset sepsis in preterm infants

P Manzoni - Clinics in perinatology, 2015 - perinatology.theclinics.com
Hematologic changes during sepsis and infection in preterm neonates are frequent and may
be seen as a diagnostic sign on one hand as well as a prognostic sign on the other hand. As …

Predictive value of red blood cell distribution width in septic shock patients with thrombocytopenia: A retrospective study using machine learning

J Ling, T Liao, Y Wu, Z Wang, H Jin… - Journal of Clinical …, 2021 - Wiley Online Library
Background Sepsis‐associated thrombocytopenia (SAT) is common in critical patients and
results in the elevation of mortality. Red cell distribution width (RDW) can reflect body …

Evaluation and management of thrombocytopenic neonates in the intensive care unit

A Del Vecchio - Early human development, 2014 - Elsevier
Thrombocytopenia is a very frequent problem among sick neonates, affecting up to 35% of
all infants admitted to the neonatal intensive care unit (NICU), and serves as an important …

[HTML][HTML] Neonatal sepsis and hemostasis

D Gialamprinou, G Mitsiakos, GN Katsaras… - Diagnostics, 2022 - mdpi.com
Neonatal sepsis is considered critical for a significant increase in neonatal morbidity and
mortality among hospitalized neonates. Neonatal sepsis, in most cases, coexists with …

[PDF][PDF] Hematological scoring system for early diagnosis of neonatal sepsis

M Saleem, KI Shah, SM Cheema… - Journal of Rawalpindi …, 2014 - scholar.archive.org
Background: To determine the accuracy of a simple and cost effective haematological
scoring system (HSS) in the early diagnosis of neonatal sepsis using blood culture as a gold …