BDNF signaling via its transmembrane receptor TrkB has an important role in neuronal
survival, differentiation, and synaptic plasticity. Remarkably, BDNF is capable of modulating …

Depression is a prevalent mental health disorder and is the number one cause of disability
worldwide. Risk factors for depression include genetic predisposition and stressful life …

Complex mechanisms control the signaling of neurotrophins through p75 NTR and Trk
receptors, allowing cellular responses that are highly context dependent, particularly in the …

Oxytocin increases the salience of both positive and negative social contexts and it is
thought that these diverse actions on behavior are mediated in part through circuit-specific …

Optimizing reproductive fitness in mammalians requires behavioral adaptations during
pregnancy. Maternal preparatory nesting is an essential behavior for the survival of the …

Brain-derived neurotrophic factor (BDNF) promotes the survival and functioning of neurons
in the central nervous system and contributes to proper functioning of many non-neural …

Parallel processing circuits are thought to dramatically expand the network capabilities of
the nervous system. Magnocellular and parvocellular oxytocin neurons have been proposed …

Brain-derived Neurotrophic Factor (BDNF) binds to the TrkB tyrosine kinase receptor, which
dictates the sensitivity of neurons to BDNF. A unique feature of TrkB is the ability to be …

Brain-derived neurotrophic factor (BDNF) controls the survival, growth, and function of
neurons both during the development and in the adult nervous system. Bdnf is transcribed …

Paternal care plays a critical role in the development of brain and behaviors in offspring in
monogamous species. However, the neurobiological mechanisms, especially the neuronal …