Bacterial battle against acidity
J Schwarz, K Schumacher, S Brameyer… - FEMS Microbiology …, 2022 - academic.oup.com
The Earth is home to environments characterized by low pH, including the gastrointestinal
tract of vertebrates and large areas of acidic soil. Most bacteria are neutralophiles, but can …
tract of vertebrates and large areas of acidic soil. Most bacteria are neutralophiles, but can …
Challenges in mucosal vaccines for the control of infectious diseases
T Azegami, Y Yuki, H Kiyono - International immunology, 2014 - academic.oup.com
The mucosal surface is the largest route through which pathogens enter the human body. To
control the outbreak of mucosal infectious diseases, we must use our knowledge of the …
control the outbreak of mucosal infectious diseases, we must use our knowledge of the …
Morphine use induces gastric microbial dysbiosis driving gastric inflammation through TLR2 signalling which is attenuated by proton pump inhibition
Abstract Background and Purpose Opioids are the standard drug for pain management;
however, their effects on gastric dysfunction are relatively understudied. Opioid users have a …
however, their effects on gastric dysfunction are relatively understudied. Opioid users have a …
Porphyromonas gingivalis Lipopolysaccharide Damages Mucosal Barrier to Promote Gastritis-Associated Carcinogenesis
M Oriuchi, S Lee, K Uno, K Sudo, K Kusano… - Digestive Diseases and …, 2024 - Springer
Background Recent epidemiological studies suggested correlation between gastric cancer
(GC) and periodontal disease. Aims We aim to clarify involvement of lipopolysaccharide of …
(GC) and periodontal disease. Aims We aim to clarify involvement of lipopolysaccharide of …
The Escherichia coli acid stress response and its significance for pathogenesis
D De Biase, PA Lund - Advances in applied microbiology, 2015 - Elsevier
Escherichia coli has a remarkable ability to survive low pH and possesses a number of
different genetic systems that enable it to do this. These may be expressed constitutively …
different genetic systems that enable it to do this. These may be expressed constitutively …
Salmonella vaccines: conduits for protective antigens
JE Clark-Curtiss, R Curtiss - The Journal of Immunology, 2018 - journals.aai.org
Vaccines afford a better and more cost-effective approach to combatting infectious diseases
than continued reliance on antibiotics or antiviral or antiparasite drugs in the current era of …
than continued reliance on antibiotics or antiviral or antiparasite drugs in the current era of …
[HTML][HTML] The mucosal immune system: From dentistry to vaccine development
H Kiyono, T Azegami - Proceedings of the Japan Academy, Series B, 2015 - jstage.jst.go.jp
The oral cavity is the beginning of the aero-digestive tract, which is covered by mucosal
epithelium continuously under the threat of invasion of pathogens, it is thus protected by the …
epithelium continuously under the threat of invasion of pathogens, it is thus protected by the …
Advances in the development of Salmonella‐based vaccine strategies for protection against Salmonellosis in humans
KT Sears, JE Galen, SM Tennant - Journal of Applied …, 2021 - academic.oup.com
Salmonella spp. are important human pathogens globally causing millions of cases of
typhoid fever and non‐typhoidal salmonellosis annually. There are only a few vaccines …
typhoid fever and non‐typhoidal salmonellosis annually. There are only a few vaccines …
Opioid use in murine model results in severe gastric pathology that may be attenuated by proton pump inhibition
Opioids are the gold standard for chronic and acute pain management; however, their
consequence on gastric function is relatively understudied. Opioid users have a higher …
consequence on gastric function is relatively understudied. Opioid users have a higher …
ZINC40099027 promotes gastric mucosal repair in ongoing aspirin-associated gastric injury by activating focal adhesion kinase
Nonsteroidal anti-inflammatory drugs cause gastric ulcers and gastritis. No drug that treats
GI injury directly stimulates mucosal healing. ZINC40099027 (ZN27) activates focal …
GI injury directly stimulates mucosal healing. ZINC40099027 (ZN27) activates focal …