Psoriasis is a chronic inflammatory skin disease characterized by accelerated tumor
necrosis factor-α/interleukin-23/interleukin-17 axis, hyperproliferation and abnormal …

Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Accumulating evidence indicates that p38 mitogen-activated protein kinase (MAPK) could
play more than one role in Alzheimer's disease (AD) pathophysiology and that patients …

Recent, many methods have been reported for the synthesis of selenium-containing
bioactive scaffolds because of their interesting reactivity and potential pharmaceutical …

Background Microglial activation plays an important role in neurodegenerative diseases by
producing several proinflammatory enzymes and proinflammatory cytokines. The phenolic …

Selenium represents an essential element for organisms as various diseases can result from
selenium deficiency. As a consequence, selenium-containing heterocycles are of …

Background Resveratrol have been known to possess many pharmacological properties
including antioxidant, cardioprotective and anticancer effects. Although current studies …

The construction of 2-amino-1, 3-selenazole skeleton was realized via the PhICl2/KSeCN-
enabled electrophilic selenocyanation of β-enaminones and β-enamino esters followed by …

β‐Hydroxybutyric acid (BHBA) has neuroprotective effects, but the underlying molecular
mechanisms are unclear. Microglial activation plays an important role in neurodegenerative …

Uncontrolled inflammation is a contributing factor to many leading causes of human
morbidity and mortality including atherosclerosis, cancer and diabetes. Se is an essential …