Leucine, a branched-chain amino acid that must be supplied in the daily diet, plays an
important role in controlling protein synthesis and regulating cell metabolism in various cell …

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear hormone receptor superfamily. The 3 PPAR isotypes, PPAR …

Peroxisome proliferator-activated receptor γ (PPARγ) plays a crucial role in adipocyte
differentiation, glucose metabolism, and other physiological processes. To further explore …

Flavonoids have been identified as the antidiabetic components in a number of traditional
ethnic remedies. However, the mechanisms whereby these compounds exert their …

FoxO transcription factors are important targets of insulin action. To better understand the
role of FoxO proteins in the liver, we created transgenic mice expressing constitutively active …

This study was designed to evaluate and compare the efficacy of infusion of Ruta
graveolens (R. graveolens) and its pharmacologically active constituent, rutin, on impaired …

There are many indications that confirm the vital role of adipocytokines and PPARγ in
diabetics. Hence, the current investigation aimed to study the modulatory effects of gallic …

To determine the effects of feeding soy or isoflavones on lipid homeostasis in early
development, weanling rats were fed AIN-93G diets made with casein, soy protein isolate …

Background and purpose: Nutrient overload leads to obesity and insulin resistance.
Pioglitazone, a selective peroxisome proliferator‐activated receptor (PPAR) γ agonist, is …

Here, we aimed to investigate whether resveratrol (RSV) can ameliorate high-fat diet (HFD)-
induced metabolic disorder in fish. Blunt snout bream (Megalobrama amblycephala) with …