Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

The perennial leguminous herb Clitoria ternatea (butterfly pea) has attracted significant
interest based on its agricultural and medical applications, which range from use as a fodder …

This Review explores the class of plant-derived macrocyclic peptides called cyclotides. We
include an account of their discovery, characterization, and distribution in the plant kingdom …

For millennia, humans have used plants for food, raw materials, and medicines, but only
within the past two centuries have we begun to connect particular plant metabolites with …

Highlights•The human proteasome is the second largest drug target class.•Few prototypic
proteases are standard tools for the discovery of novel inhibitors.•Peptide protease inhibitors …

Cyclotides are plant-derived cyclic peptides that have a head-to-tail cyclic backbone and
three conserved disulphide bonds that form a cyclic cystine knot motif. They occur in plants …

Disulfide-rich cyclic peptides have exciting potential as leads or frameworks in drug
discovery; however, their use is faced with some synthetic challenges, mainly associated …

New findings• What is the topic of this review? This article describes the discovery and
function of invertebrate oxytocin and vasopressin neuropeptides.• What advances does it …

Abstract Ethnopharmacological relevance Heartsease (Viola tricolor L.), a member of the
Violaceae family, has a long history as a medicinal plant and has been documented in the …

• Premise of the study: The pantropical, species‐rich Psychotrieae and Palicoureeae are
sister tribes of mostly drupe‐bearing and nonbacterial leaf‐nodulating species with …