[HTML][HTML] Interactions of SARS-CoV-2 with the blood–brain barrier
Emerging data indicate that neurological complications occur as a consequence of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …
Cerebral vascular disease and neurovascular injury in ischemic stroke
The consequences of cerebrovascular disease are among the leading health issues
worldwide. Large and small cerebral vessel disease can trigger stroke and contribute to the …
worldwide. Large and small cerebral vessel disease can trigger stroke and contribute to the …
[HTML][HTML] Stepwise recruitment of transcellular and paracellular pathways underlies blood-brain barrier breakdown in stroke
Brain endothelial cells form a paracellular and transcellular barrier to many blood-borne
solutes via tight junctions (TJs) and scarce endocytotic vesicles. The blood-brain barrier …
solutes via tight junctions (TJs) and scarce endocytotic vesicles. The blood-brain barrier …
The Blood–Brain Barrier: Composition, Properties, and Roles in Brain Health
Blood vessels are critical to deliver oxygen and nutrients to tissues and organs throughout
the body. The blood vessels that vascularize the central nervous system (CNS) possess …
the body. The blood vessels that vascularize the central nervous system (CNS) possess …
Modern methods for delivery of drugs across the blood–brain barrier
Y Chen, L Liu - Advanced drug delivery reviews, 2012 - Elsevier
The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …
The blood-brain barrier/neurovascular unit in health and disease
BT Hawkins, TP Davis - Pharmacological reviews, 2005 - ASPET
The blood-brain barrier (BBB) is the regulated interface between the peripheral circulation
and the central nervous system (CNS). Although originally observed by Paul Ehrlich in 1885 …
and the central nervous system (CNS). Although originally observed by Paul Ehrlich in 1885 …
[HTML][HTML] Oxidative stress and the use of antioxidants in stroke
R Shirley, ENJ Ord, LM Work - Antioxidants, 2014 - mdpi.com
Transient or permanent interruption of cerebral blood flow by occlusion of a cerebral artery
gives rise to an ischaemic stroke leading to irreversible damage or dysfunction to the cells …
gives rise to an ischaemic stroke leading to irreversible damage or dysfunction to the cells …
Modelling of the blood–brain barrier in drug discovery and development
R Cecchelli, V Berezowski, S Lundquist… - Nature reviews Drug …, 2007 - nature.com
The market for neuropharmaceuticals is potentially one of the largest sectors of the global
pharmaceutical market owing to the increase in average life expectancy and the fact that …
pharmaceutical market owing to the increase in average life expectancy and the fact that …
In vitro models of the blood-brain barrier
The blood-brain barrier (BBB) is an active interface between the circulation and the central
nervous system (CNS) with a dual function: the barrier function restricts the transport from …
nervous system (CNS) with a dual function: the barrier function restricts the transport from …
[HTML][HTML] Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral …
K Sun, J Fan, J Han - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are
conditions with high mortality and serious long-term physical and cognitive disabilities. They …
conditions with high mortality and serious long-term physical and cognitive disabilities. They …