[HTML][HTML] Environmental arsenic exposure: from genetic susceptibility to pathogenesis

BC Minatel, AP Sage, C Anderson, R Hubaux… - Environment …, 2018 - Elsevier
More than 200 million people in 70 countries are exposed to arsenic through drinking water.
Chronic exposure to this metalloid has been associated with the onset of many diseases …

[HTML][HTML] Impact of gene–environment interactions on cancer development

A Mbemi, S Khanna, S Njiki, CG Yedjou… - International journal of …, 2020 - mdpi.com
Several epidemiological and experimental studies have demonstrated that many human
diseases are not only caused by specific genetic and environmental factors but also by gene …

[HTML][HTML] Arsenic-induced genotoxicity and genetic susceptibility to arsenic-related pathologies

F Faita, L Cori, F Bianchi, MG Andreassi - International journal of …, 2013 - mdpi.com
The arsenic (As) exposure represents an important problem in many parts of the World.
Indeed, it is estimated that over 100 million individuals are exposed to arsenic, mainly …

Toenails as a biomarker of exposure to arsenic: A review

AJ Signes-Pastor, E Gutiérrez-González… - Environmental …, 2021 - Elsevier
This systematic review summarizes the current evidence related to the reliability of toenail
total arsenic concentrations (thereafter “arsenic”) as a biomarker of long-term exposure …

AS3MT, GSTO, and PNP polymorphisms: impact on arsenic methylation and implications for disease susceptibility

R Antonelli, K Shao, DJ Thomas, R Sams II… - Environmental …, 2014 - Elsevier
Background Oral exposure to inorganic arsenic (iAs) is associated with adverse health
effects. Epidemiological studies suggest differences in susceptibility to these health effects …

[图书][B] Arsenic in groundwater: poisoning and risk assessment

MM Hassan - 2018 - taylorfrancis.com
Arsenic-contaminated groundwater is considered one of the world's largest environmental
health crises, as more than 300 million people in more than one-third of countries worldwide …

Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformation

K Lu, PH Cable, RP Abo, H Ru… - Chemical research in …, 2013 - ACS Publications
Exposure to arsenic affects large human populations worldwide and has been associated
with a long list of human diseases, including skin, bladder, lung, and liver cancers, diabetes …

Role of aquaglyceroporins and caveolins in energy and metabolic homeostasis

L Méndez-Giménez, A Rodríguez, I Balaguer… - Molecular and Cellular …, 2014 - Elsevier
Aquaglyceroporins and caveolins are submicroscopic integral membrane proteins that are
particularly abundant in many mammalian cells. Aquaglyceroporins (AQP3, AQP7, AQP9 …

[HTML][HTML] As3MT and GST polymorphisms influencing arsenic metabolism in human exposure to drinking groundwater

F González-Martínez, D Sánchez-Rodas… - International Journal of …, 2020 - mdpi.com
The urinary arsenic metabolites may vary among individuals and the genetic factors have
been reported to explain part of the variation. We assessed the influence of polymorphic …

Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N‐6 adenine‐specific DNA methyltransferase 1 (N6AMT1) polymorphisms …

R De la Rosa, C Steinmaus, NK Akers… - Environmental and …, 2017 - Wiley Online Library
Inter‐individual differences in arsenic metabolism have been linked to arsenic‐related
disease risks. Arsenic (+ 3) methyltransferase (AS3MT) is the primary enzyme involved in …