The expressive number of deaths and confirmed cases of SARS-CoV-2 call for an urgent
demand of effective and available drugs for COVID-19 treatment. CD147, a receptor on host …

The combat against the Corona virus disease of 2019 (COVID-19), has created a chaos
among the healthcare institutions and researchers, in turn accelerating the dire need to …

Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

Abstract The Strategic Plan for Biodefense Research by the US Department of Health and
Human Services demarcates the need for drugs which target multiple types of pathogens to …

Lymphopenia is considered one of the most characteristic clinical features of the coronavirus
disease 2019 (COVID-19). SARS-CoV-2 infects host cells via the interaction of its spike …

With advances in sequencing technology, uncharacterized proteins and domains of
unknown function (DUFs) are rapidly accumulating in sequence databases and offer an …

Regulated exocytosis by secretory organelles is important for malaria parasite invasion and
egress. Many parasite effector proteins, including perforins, adhesins, and proteases, are …

Chloroplasts are cellular organelles of plants and algae that are responsible for energy
conversion and carbon fixation by the photosynthetic reaction. As a consequence of their …

Abstract Classical macrolides containing 14-or 15-membered aglycone lactone rings are
basic and widely used antibacterial agents in clinical therapy. Macrolides exert antibacterial …

Plasmodium spp. parasites that cause malaria disease remain a significant global-health
burden. With the spread of parasites resistant to artemisinin combination therapies in …