[HTML][HTML] From transplant to novel cellular therapies in multiple myeloma: European Myeloma Network guidelines and future perspectives

F Gay, M Engelhardt, E Terpos, R Wäsch… - …, 2018 - ncbi.nlm.nih.gov
Survival of myeloma patients has greatly improved with the use of autologous stem cell
transplantation and novel agents, such as proteasome inhibitors, immunomodulatory drugs …

Maintenance therapy in AML: the past, the present and the future

M Molica, M Breccia, R Foa, E Jabbour… - American journal of …, 2019 - Wiley Online Library
Curative treatment in acute myeloid leukemia (AML) depends on successful induction
therapy to achieve a complete remission (CR), and subsequent post‐remission therapy to …

Multiple myeloma, version 3.2021, NCCN clinical practice guidelines in oncology

SK Kumar, NS Callander, K Adekola… - Journal of the National …, 2020 - jnccn.org
Multiple myeloma is a malignant neoplasm of plasma cells that accumulate in bone marrow,
leading to bone destruction and marrow failure. This manuscript discusses the management …

PD-1 blockade for relapsed lymphoma post–allogeneic hematopoietic cell transplant: high response rate but frequent GVHD

BM Haverkos, D Abbott, M Hamadani… - Blood, The Journal …, 2017 - ashpublications.org
Given the limited treatment options for relapsed lymphoma post–allogeneic hematopoietic
cell transplantation (post–allo-HCT) and the success of programmed death 1 (PD-1) …

Multiple myeloma, version 3.2017, NCCN clinical practice guidelines in oncology

SK Kumar, NS Callander, M Alsina… - Journal of the National …, 2017 - jnccn.org
Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These
neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone …

[HTML][HTML] American society of blood and marrow transplantation, european society of blood and marrow transplantation, blood and marrow transplant clinical trials …

S Giralt, L Garderet, B Durie, G Cook, G Gahrton… - Biology of Blood and …, 2015 - Elsevier
In contrast to the upfront setting in which the role of high-dose therapy with autologous
hematopoietic cell transplantation (HCT) as consolidation of a first remission in patients with …

Lenalidomide enhances anti-myeloma cellular immunity

K Luptakova, J Rosenblatt, B Glotzbecker… - Cancer immunology …, 2013 - Springer
Lenalidomide is an effective therapeutic agent for multiple myeloma that exhibits
immunomodulatory properties including the activation of T and NK cells. The use of …

[HTML][HTML] Hematopoietic stem cell transplantation for multiple myeloma: guidelines from the American Society for Blood and Marrow Transplantation

N Shah, N Callander, S Ganguly, Z Gul… - Biology of Blood and …, 2015 - Elsevier
Therapeutic strategies for multiple myeloma (MM) have changed dramatically over the past
decade. Thus, the role of hematopoietic stem cell transplantation (HCT) must be considered …

A clinical perspective on plasma cell leukemia; current status and future directions

SA Tuazon, LA Holmberg, O Nadeem… - Blood Cancer …, 2021 - nature.com
Primary plasma cell leukemia (pPCL) is an aggressive plasma cell disorder with a guarded
prognosis. The diagnosis is confirmed when peripheral blood plasma cells (PCs) exceed …

Treatment of AML relapse after allo-HCT

JA Webster, L Luznik, I Gojo - Frontiers in Oncology, 2021 - frontiersin.org
With advances in allogeneic hematopoietic stem cell transplant (allo-HCT), disease relapse
has replaced transplant-related mortality as the primary cause of treatment failure for …