Lutein and docosahexaenoic acid prevent cortex lipid peroxidation in streptozotocin-induced diabetic rat cerebral cortex

E Arnal, M Miranda, J Barcia, F Bosch-Morell… - Neuroscience, 2010 - Elsevier
The mechanisms underlying diabetic encephalopathy, are largely unknown. Here, we
examined whether docosahexaenoic acid (DHA) and lutein could attenuate the oxidative …

Effects of extended-release 7-nitroindazole gel formulation treatment on the behavior of Shank3 mouse model of autism

M Abdel-Haq, SK Ojha, W Hamoudi, A Kumar… - Nitric Oxide, 2023 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
behavioral deficits such as abnormalities in communication, social interaction, anxiety, and …

Coordination chemistry of nitrosyls and its biochemical implications

H Lewandowska - … Complexes in Inorganic Chemistry, Biochemistry and …, 2014 - Springer
A comprehensive overview is presented of the biologically relevant coordination chemistry
of nitrosyls and its biochemical consequences. Representative classes of metal nitrosyls are …

Cannabinoid and nitric oxide signaling interplay in the modulation of hippocampal hyperexcitability: study on electrophysiological and behavioral models of temporal …

F Carletti, G Gambino, V Rizzo, G Ferraro, P Sardo - Neuroscience, 2015 - Elsevier
A growing bulk of evidence suggests that cannabinoid system plays a pivotal role in the
control of hyperexcitability phenomena. Notwithstanding, the anticonvulsant action of …

Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant

A Fujimoto, Y Shingai, TB Oyama, T Kawanai… - Toxicology in Vitro, 2010 - Elsevier
Many effects of sesamol, an antioxidative constituent of sesame oil, have been reported for
human health benefits due to its antioxidative action. However, we recently isolated two …

Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by …

T Herraiz, VJ Aran, H Guillen - Free radical research, 2009 - Taylor & Francis
Monoamine oxidase (MAO) B is a mitochondrial enzyme selectively involved in the oxidative
activation of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) neurotoxin to toxic …

Coordination of iron ions in the form of histidinyl dinitrosyl complexes does not prevent their genotoxicity

H Lewandowska, TM Stępkowski, J Sadło… - Bioorganic & medicinal …, 2012 - Elsevier
Formation of dinitrosyl iron complexes (DNICs) was observed in a wide spectrum of
pathophysiological conditions associated with overproduction of NO. To gain insight into the …

Formation of glutathionyl dinitrosyl iron complexes protects against iron genotoxicity

H Lewandowska, J Sadło, S Męczyńska… - Dalton …, 2015 - pubs.rsc.org
Dinitrosyl iron (I) complexes (DNICs), intracellular NO donors, are important factors in nitric
oxide-dependent regulation of cellular metabolism and signal transduction. It has been …

Cystamine attenuates the expressions of NOS-and TLR-associated molecules in the brain of NZB/W F1 mice

HP Wang, TC Hsu, GJ Hsu, SL Li, BS Tzang - European journal of …, 2009 - Elsevier
Evidence have indicated the impairment of central nervous system (CNS) and
neuropsychiatric disorder in patients with systemic lupus erythematosus (SLE). However …

[PDF][PDF] ROLE OF NITRIC OXIDE/cGMP PATHWAY IN CANNABINOID MODULATION OF PAROXYSMAL PHENOMENA

DSSAG GAMBINO, CH MA, SSAF FARINA, CH MO… - 2017 - iris.unipa.it
Epilepsy is broadly recognized as a multi-factorial neurologic disorder, defined by a state of
recurrent, spontaneous seizures (Stafstrom and Carmant, 2015). In patients, epileptic …