Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences

I Steuer, PA Guertin - Reviews in the Neurosciences, 2019 - degruyter.com
Central pattern generators (CPGs) are generally defined as networks of neurons capable of
enabling the production of central commands, specifically controlling stereotyped, rhythmic …

Rehabilitation strategies after spinal cord injury: inquiry into the mechanisms of success and failure

MP Côté, M Murray, MA Lemay - Journal of neurotrauma, 2017 - liebertpub.com
Body-weight supported locomotor training (BWST) promotes recovery of load-bearing
stepping in lower mammals, but its efficacy in individuals with a spinal cord injury (SCI) is …

A review on locomotor training after spinal cord injury: reorganization of spinal neuronal circuits and recovery of motor function

AC Smith, M Knikou - Neural plasticity, 2016 - Wiley Online Library
Locomotor training is a classic rehabilitation approach utilized with the aim of improving
sensorimotor function and walking ability in people with spinal cord injury (SCI). Recent …

Plantar cutaneous sensitivity and balance in individuals with and without chronic ankle instability

MR Powell, CJ Powden, MN Houston… - Clinical journal of sport …, 2014 - journals.lww.com
Objective: To determine if plantar cutaneous sensation and postural control differ between
individuals with and without chronic ankle instability (CAI). Design: Case–control. Setting …

Neural control of locomotion and training-induced plasticity after spinal and cerebral lesions

M Knikou - Clinical Neurophysiology, 2010 - Elsevier
Standing and walking require a plethora of sensorimotor interactions that occur throughout
the nervous system. Sensory afferent feedback plays a crucial role in the rhythmical muscle …

Locomotor training improves premotoneuronal control after chronic spinal cord injury

M Knikou, CK Mummidisetty - Journal of neurophysiology, 2014 - journals.physiology.org
Spinal inhibition is significantly reduced after spinal cord injury (SCI) in humans. In this work,
we examined if locomotor training can improve spinal inhibition exerted at a presynaptic …

Direct evidence for decreased presynaptic inhibition evoked by PBSt group I muscle afferents after chronic SCI and recovery with step‐training in rats

G Caron, JN Bilchak, MP Côté - The Journal of physiology, 2020 - Wiley Online Library
Key points Presynaptic inhibition is modulated by supraspinal centres and primary afferents
in order to filter sensory information, adjust spinal reflex excitability, and ensure smooth …

Plasticity of corticospinal neural control after locomotor training in human spinal cord injury

M Knikou - Neural plasticity, 2012 - Wiley Online Library
Spinal lesions substantially impair ambulation, occur generally in young and otherwise
healthy individuals, and result in devastating effects on quality of life. Restoration of …

Brain and spinal cord paired stimulation coupled with locomotor training affects polysynaptic flexion reflex circuits in human spinal cord injury

TS Pulverenti, M Zaaya, M Knikou - Experimental brain research, 2022 - Springer
Neurorecovery from locomotor training is well established in human spinal cord injury (SCI).
However, neurorecovery resulting from combined interventions has not been widely studied …

Functional reorganization of soleus H-reflex modulation during stepping after robotic-assisted step training in people with complete and incomplete spinal cord injury

M Knikou - Experimental Brain Research, 2013 - Springer
Body weight–supported (BWS) robotic-assisted step training on a motorized treadmill is
utilized with the aim to improve walking ability in people after damage to the spinal cord …