The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

Claudins are tight junction membrane proteins that are expressed in epithelia and
endothelia and form paracellular barriers and pores that determine tight junction …

The tight junction creates an intercellular barrier limiting paracellular movement of solutes
and material across epithelia. Currently many proteins have been identified as components …

The tight junction forms a barrier against unlimited paracellular passage but some of the
tight junction proteins just do the opposite, they form extracellular channels zigzagging …

Claudins are tetraspan transmembrane proteins of tight junctions. They determine the
barrier properties of this type of cell–cell contact existing between the plasma membranes of …

▪ Abstract Tight junctions form continuous intercellular contacts controlling solute movement
through the paracellular pathway across epithelia. Paracellular barriers vary among …

An immature intestinal epithelial barrier may predispose infants and children to many
intestinal inflammatory diseases, such as infectious enteritis, inflammatory bowel disease …

The uroepithelium sits at the interface between the urinary space and underlying tissues,
where it forms a high-resistance barrier to ion, solute, and water flux, as well as pathogens …

Tight junctions contribute to the paracellular barrier, the fence dividing plasma membranes,
and signal transduction, acting as a multifunctional complex in vertebrate epithelial and …

The epithelial barrier is fundamental to the physiology of most metazoan organ systems.
Occluding junctions, including vertebrate tight junctions and invertebrate septate junctions …