Obesity and cancer: inflammation bridges the two

R Kolb, FS Sutterwala, W Zhang - Current opinion in pharmacology, 2016 - Elsevier
Highlights•Obesity is associated with chronic inflammation and chronic diseases.•Obesity is
associated with increased risk and progression of several cancers.•The mechanism by …

Postdiagnosis body fatness, weight change and breast cancer prognosis: Global Cancer Update Program (CUP global) systematic literature review and meta‐analysis

DSM Chan, R Vieira, L Abar, D Aune… - … Journal of Cancer, 2023 - Wiley Online Library
Previous evidence on postdiagnosis body fatness and mortality after breast cancer was
graded as limited‐suggestive. To evaluate the evidence on body mass index (BMI), waist …

[HTML][HTML] Obesity and breast cancer: a case of inflamed adipose tissue

R Kolb, W Zhang - Cancers, 2020 - mdpi.com
Obesity is associated with an increased risk of estrogen receptor-positive breast cancer in
postmenopausal women and a worse prognosis for all major breast cancer subtypes …

[HTML][HTML] Body mass index and prognosis of breast cancer: An analysis by menstruation status when breast cancer diagnosis

L Sun, Y Zhu, Q Qian, L Tang - Medicine, 2018 - journals.lww.com
Objective: To examine whether obesity/overweight is a risk predictor for breast cancer
recurrence and death by menopausal status in a retrospective study. Methods: We …

VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis

CW Lu, YH Lo, CH Chen, CY Lin, CH Tsai, PJ Chen… - Cancer letters, 2017 - Elsevier
Abnormal lipoprotein profiles are associated with breast cancer progression. However, the
mechanisms linking abnormal lipoprotein levels to breast cancer progression, especially …

[HTML][HTML] Adipocyte-derived exosomes promote lung cancer metastasis by increasing MMP9 activity via transferring MMP3 to lung cancer cells

J Wang, Y Wu, J Guo, X Fei, L Yu, S Ma - Oncotarget, 2017 - ncbi.nlm.nih.gov
Obesity is involved in tumor progression. However, the corresponding mechanisms remain
largely unknown. Here, we report that adipocytes increase the invasive ability of tumor cells …

[HTML][HTML] Breast cancer risk factors in Iran: a systematic review & meta-analysis

A Shamshirian, K Heydari, Z Shams… - … molecular biology and …, 2020 - degruyter.com
Objectives Breast cancer is known as one of the deadliest forms of cancer, and it is
increasing globally. There are a variety of proven and controversial risk factors for this …

Impact of obesity on clinicopathologic characteristics and disease prognosis in pre‐and postmenopausal breast cancer patients: a retrospective institutional study

NM Ayoub, RJ Yaghan, NM Abdo, II Matalka… - Journal of …, 2019 - Wiley Online Library
Purpose. To investigate the association between obesity and breast cancer
clinicopathologic characteristics at presentation along with prognostic impact among …

[HTML][HTML] Leptin induces cell migration and invasion in a FAK-Src-dependent manner in breast cancer cells

JC Juárez-Cruz, MD Zuñiga-Eulogio… - Endocrine …, 2019 - ec.bioscientifica.com
Breast cancer is the most common invasive neoplasia, and the second leading cause of the
cancer deaths in women worldwide. Mammary tumorigenesis is severely linked to obesity …

[HTML][HTML] Body mass index increases the lymph node metastasis risk of breast cancer: a dose-response meta-analysis with 52904 subjects from 20 cohort studies

J Wang, Y Cai, F Yu, Z Ping, L Liu - BMC cancer, 2020 - Springer
Background Since body mass index (BMI) is a convincing risk factor for breast cancer, it is
speculated to be associated with lymph node metastasis. However, epidemiological studies …