Drosophila olfaction as a model system for studying human neurological disorders

S Sarkar, A Das - Journal of Biosciences, 2023 - Springer
The fruit fly, Drosophila melanogaster, has been one of the finest systems for decoding
myriad puzzles across different domains of biology. Beyond addressing the fundamental …

[HTML][HTML] Neuroprotective, lifespan and memory enhancing potential, and molecular docking studies of natural compound from Curculigo orchioides: A study on …

GK Pratap, PG Nagaraju, A Danagoudar… - South African Journal of …, 2022 - Elsevier
Alzheimer's (AD) is one of the most common age-related neurodegenerative diseases in the
world. Currently it has affected about 33.9 million people and is estimated to triple over the …

Ameliorative activity of medicinal plant fraction for neuroprotection against acrylamide-induced neurotoxicity in Drosophila melanogaster—a comparative study

GK Pratap, D Ananda, CG Joshi… - The Journal of Basic and …, 2021 - Springer
Background Medicinal plant extracts used in folk medicine seem to be crucial since those
are generally accepted by people without worrying about the toxicity. In our present study …

A Role for Drosophila Amyloid Precursor Protein in Retrograde Trafficking of L1-Type Cell Adhesion Molecule Neuroglian

T Penserga, SR Kudumala, R Poulos… - Frontiers in cellular …, 2019 - frontiersin.org
The role of the Amyloid Precursor Protein (APP) in the pathology of Alzheimer's disease
(AD) has been well studied. However, the normal function of APP in the nervous system is …

APP and β-amyloid modulate protein aggregation and dissociation from recycling endosomal and exosomal membranes

PJ Singh, B Verma, A Wells, CC Mendes, D Dunn… - bioRxiv, 2024 - biorxiv.org
Secretory proteins frequently aggregate into non-soluble dense-core granules (DCGs) in
recycling endosome-like compartments prior to release. By contrast, aberrantly processed …

Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model

K Furotani, K Kamimura, T Yajima, M Nakayama… - PLoS …, 2018 - journals.plos.org
APP (amyloid precursor protein), the causative molecule of Alzheimer's disease, is
synthesized in neuronal cell bodies and subsequently transported to synapses. We …

Marketing digital y la experiencia de compra en los clientes de la empresa GNIX SRL-Lima, 2022

J Manuel Ruiz, KM Rodriguez Ramirez - 2022 - repositorio.ucv.edu.pe
El presente estudio propuso como objetivo establecer en qué medida se relaciona el
marketing digital y la experiencia de compra en los clientes de la empresa G-NIX SRL-Lima …

Investigating Amyloid β toxicity in Drosophila melanogaster

M Jonson - 2017 - diva-portal.org
In this thesis Drosophila melanogaster (the fruit fly) has been used as a model organism to
study the aggregation and toxic properties of the human amyloid β (Aβ) peptide involved in …

[PDF][PDF] Drosophila melanogaster–модельна система для вивчення нейропатій людини та тестування нейропротекторних засобів

НП Матійців, ЯІ Черник - Цитологія і генетика, 2020 - jnas.nbuv.gov.ua
На сьогодні молекулярні характеристики виникнення та перебігу нейродегенеративних
захворювань–одних із найважчих і наразі невиліковних–залишаються не до кінця …

Drosophila melanogaster as a Model System for the Study of Human Neuropathy and the Testing of Neuroprotectors

NP Matiytsiv, YI Chernyk - Cytology and Genetics, 2020 - Springer
Currently, the molecular characteristics of the occurrence and course of neurodegenerative
diseases, which are among the most serious and still incurable illnesses, remain to be fully …