A Mini-Review on the Common Antiviral Drug Targets of Coronavirus

J Wang, Q Zhu, X Xing, D Sun - Microorganisms, 2024 - mdpi.com
Coronaviruses in general are a zoonotic pathogen with significant cross-species
transmission. They are widely distributed in nature and have recently become a major threat …

[HTML][HTML] SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants

SS Hassan, T Bhattacharya, D Nawn, I Jha… - Computers in Biology …, 2024 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the rapidly evolving RNA
virus behind the COVID-19 pandemic, has spawned numerous variants since its 2019 …

Structure-Based Virtual Screening for Methyltransferase Inhibitors of SARS-CoV-2 nsp14 and nsp16

K Wu, Y Guo, T Xu, W Huang, D Guo, L Cao, J Lei - Molecules, 2024 - mdpi.com
The ongoing COVID-19 pandemic still threatens human health around the world. The
methyltransferases (MTases) of SARS-CoV-2, specifically nsp14 and nsp16, play crucial …

SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery

V Kremling, S Falke, Y Fernandez-Garcia, C Ehrt… - bioRxiv, 2024 - biorxiv.org
Non-structural protein 10 (nsp10) and non-structural protein 16 (nsp16) are part of the RNA
synthesis complex, which is crucial for the replication of severe acute respiratory syndrome …

[PDF][PDF] S-adenosylmethionine therapy in rheumatic and related autoimmune diseases

JF de Carvalho, LP Churilov, A Lerner… - 2023 - dspace.spbu.ru
S-adenosylmethionine has been used to treat neuropsychiatric diseases, including those
accompanied with depression. These entities often are comorbid with rheumatic and thyroid …

S-adenosylmethionine therapy in rheumatic and related autoimmune diseases

Л Чурилов, ЖФ де Карвальо… - Вестник Санкт …, 2023 - medicine-journal.spbu.ru
Вестник СПбГУ. Медицина. 2023. Т. 18. Вып. 4 349 therapy supplementation, including 2
papers documented positive effect in vitro achieved upon the cells taken from patients. Most …