The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Amyloid oligomers: A joint experimental/computational perspective on Alzheimer's disease, Parkinson's disease, type II diabetes, and amyotrophic lateral sclerosis

PH Nguyen, A Ramamoorthy, BR Sahoo… - Chemical …, 2021 - ACS Publications
Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Enhanced optical asymmetry in supramolecular chiroplasmonic assemblies with long-range order

J Lu, Y Xue, K Bernardino, NN Zhang, WR Gomes… - Science, 2021 - science.org
Chiral assemblies of plasmonic nanoparticles are known for strong circular dichroism but not
for high optical asymmetry, which is limited by the unfavorable combination of electrical and …

Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer's disease

K Hou, J Zhao, H Wang, B Li, K Li, X Shi, K Wan… - Nature …, 2020 - nature.com
Preventing aggregation of amyloid beta (Aβ) peptides is a promising strategy for the
treatment of Alzheimer's disease (AD), and gold nanoparticles have previously been …

Nanoparticle toxicology

W Yang, L Wang, EM Mettenbrink… - Annual Review of …, 2021 - annualreviews.org
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …

Air pollution, ultrafine particles, and your brain: are combustion nanoparticle emissions and engineered nanoparticles causing preventable fatal neurodegenerative …

L Calderón-Garcidueñas, A Ayala - Environmental science & …, 2022 - ACS Publications
Exposure to particulate matter (PM) pollution damages the human brain. Fossil fuel burning
for transportation energy accounts for a significant fraction of urban air and climate pollution …

Dependence of nanoparticle toxicity on their physical and chemical properties

A Sukhanova, S Bozrova, P Sokolov… - Nanoscale research …, 2018 - Springer
Studies on the methods of nanoparticle (NP) synthesis, analysis of their characteristics, and
exploration of new fields of their applications are at the forefront of modern nanotechnology …

Crossing the blood-brain barrier with nanoparticles

Y Zhou, Z Peng, ES Seven, RM Leblanc - Journal of controlled release, 2018 - Elsevier
The blood-brain barrier (BBB) is one of the most essential protection mechanisms in the
central nervous system (CNS). It selectively allows individual molecules such as small lipid …

Nanomaterials in the environment: behavior, fate, bioavailability, and effects—an updated review

JR Lead, GE Batley, PJJ Alvarez… - Environmental …, 2018 - Wiley Online Library
The present review covers developments in studies of nanomaterials (NMs) in the
environment since our much cited review in 2008. We discuss novel insights into fate and …