Stimuli-responsive nanoassemblies for targeted delivery against tumor and its microenvironment
Despite the emergence of various cancer treatments, such as surgery, chemotherapy,
radiotherapy, and immunotherapy, their use remains restricted owing to their limited tumor …
radiotherapy, and immunotherapy, their use remains restricted owing to their limited tumor …
Specific recognition to create nanofunctionalized cells for precise functions
TK Zhang, W Geng, YQ Huang, FZ Wang, G Tian… - Coordination Chemistry …, 2024 - Elsevier
Specific recognition sites exist in cells to bring about encapsulation and consequent
enhancements in stability and selectivity. Methods to create nanofunctionalized cells have …
enhancements in stability and selectivity. Methods to create nanofunctionalized cells have …
[HTML][HTML] Flavonoid-based nanomedicines to target tumor microenvironment
Cancer cells arise and grow in tumor microenvironment which consists of stromal cells and
extracellular matrix. The dynamic interaction between cancer cells and different components …
extracellular matrix. The dynamic interaction between cancer cells and different components …
[HTML][HTML] Mannose-coated reconstituted lipoprotein nanoparticles for the targeting of tumor-associated macrophages: optimization, characterization, and in vitro …
AS Dossou, ME Mantsch, A Kapic, WL Burnett… - Pharmaceutics, 2023 - mdpi.com
Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as
delivery vehicles to a variety of targets, including cancer cells. However, the modification of …
delivery vehicles to a variety of targets, including cancer cells. However, the modification of …
TAM‐Hijacked Immunoreaction Rescued by Hypoxia‐Pathway‐Intervened Strategy for Enhanced Metastatic Cancer Immunotherapy
T Jiang, B Wang, T Wang, L Zhang, X Chen, X Zhao - Small, 2024 - Wiley Online Library
Immunotherapy is regarded as a prospective strategy against metastatic cancer. However,
tumor‐associated macrophages (TAMs), which accumulate in hypoxic tumor …
tumor‐associated macrophages (TAMs), which accumulate in hypoxic tumor …
Intraperitoneal administration of PLGA nanoparticles could deliver the cargo to tumor-associated macrophages with less spreading peritoneal macrophages in the …
The survival time of patients with peritoneal metastasis is limited despite all treatments.
Recent studies revealed that tumor-associated macrophages (TAMs) are educated in the …
Recent studies revealed that tumor-associated macrophages (TAMs) are educated in the …