Paget's disease: a review of the epidemiology, etiology, genetics, and treatment

B Banaganapalli, I Fallatah, F Alsubhi, PJ Shetty… - Frontiers in …, 2023 - frontiersin.org
Paget's disease of bone (PDB) is the second most prevalent metabolic bone disorder
worldwide, with a prevalence rate of 1.5%–8.3%. It is characterized by localized areas of …

Genetic determinants of Paget's disease of bone

NS Makaram, SH Ralston - Current osteoporosis reports, 2021 - Springer
Abstract Purpose of Review To provide an overview of the role of genes and loci that
predispose to Paget's disease of bone and related disorders. Recent Findings Studies over …

A mutation in the ZNF687 gene that is responsible for the severe form of Paget's disease of bone causes severely altered bone remodeling and promotes …

S Russo, F Scotto di Carlo, A Maurizi, G Fortunato… - Bone Research, 2023 - nature.com
Paget's disease (PDB) is a late-onset bone remodeling disorder with a broad spectrum of
symptoms and complications. One of the most aggressive forms is caused by the P937R …

[HTML][HTML] Outcomes following total hip and knee arthroplasty in patients who have Paget's disease of bone: a systematic review

M Arif, NS Makaram, GJ Macpherson… - The Journal of …, 2023 - Elsevier
Abstract Background Patients who have Paget's Disease more frequently require total hip
arthroplasty (THA) and total knee arthroplasty (TKA) than matched controls. However …

Clinical and radiological outcomes of total hip arthroplasty in patients affected by Paget's disease: a combined registry and single-institution retrospective …

A Di Martino, MAR Coppola, B Bordini… - Journal of Orthopaedics …, 2021 - Springer
Background Total hip arthroplasty (THA) in patients with Paget's disease can be associated
with technical difficulties related to deformities and altered mechanical bone properties, and …

Paget's Disease of the Bone and Lynch Syndrome: An Exceptional Finding

AM Gheorghe, LS Stanescu, E Petrova, M Carsote… - Diagnostics, 2023 - mdpi.com
Our objective is to present an exceptional case of a patient diagnosed with Paget's disease
of the bone (PDB) while being confirmed with Lynch syndrome (LS). A 44-year-old woman …

Total elbow arthroplasty for elbow osteoarthritis associated with Paget's disease: A case report and review of literature

J Hasler, U Riede, N Helmy… - JSES Reviews, Reports …, 2023 - pmc.ncbi.nlm.nih.gov
journal homepage: www. jsesreviewsreportstech. org https://doi. org/10.1016/j. xrrt. 2023.10.
002 2666-6391/© 2023 The Authors. Published by Elsevier Inc. on behalf of American …

[HTML][HTML] Total hip arthroplasty and Paget's disease: case report and literature review

C Cardile, C Cazzaniga, A Mosca… - Acta Bio Medica: Atenei …, 2022 - ncbi.nlm.nih.gov
Paget's disease (PDB) is a chronic osteopathy more common in male, Caucasic, European
population, after the age of 50 years, that can lead to bone deformities. A challenging …

The ZNF687 mutation of Paget's disease associated with giant cell tumour causes severe bone remodelling alteration as a result of a deregulated osteoclast …

S Russo, FS di Carlo, G Fortunato, A Maurizi, A Teti… - bioRxiv, 2022 - biorxiv.org
Paget's disease (PDB) is a late-onset bone remodelling disorder with a broad spectrum of
symptoms and complications. One of the most aggressive forms is caused by the P937R …

Bilateral Cemented Custom-Made Total Hip Arthroplasty in Paget's Disease with Femoral Cortical Thickening and Canal Narrowing

R D'Ambrosi, L Ballini, F Valli, S Guarino, M Rubino… - Joints, 2019 - thieme-connect.com
In this report, we present a case of a 57-year-old man complaining of pain in both his hips.
Clinically, the patient reported lameness and reduction in the range of motion of the hips …