Moonlight functions of glycolytic enzymes in cancer

PV Shegay, OP Shatova, AA Zabolotneva… - Frontiers in Molecular …, 2023 - frontiersin.org
Since an extensive genome research has started, basic principle “one gene—one protein—
one function” was significantly revised. Many proteins with more than one function were …

Glucometabolic reprogramming: From trigger to therapeutic target in hepatocellular carcinoma

H Xia, Z Huang, Z Wang, S Liu, X Zhao, J You… - Frontiers in …, 2022 - frontiersin.org
Glucose, the central macronutrient, releases energy as ATP through carbon bond oxidation
and supports various physiological functions of living organisms. Hepatocarcinogenesis …

ALDOC-and ENO2-driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis

C De Vitis, AM Battaglia, M Pallocca… - Journal of Experimental …, 2023 - Springer
Background Metastases are the major cause of cancer-related morbidity and mortality. By
the time cancer cells detach from their primary site to eventually spread to distant sites, they …

Mass spectrometry in cerebrospinal fluid uncovers association of glycolysis biomarkers with Alzheimer's disease in a large clinical sample

MB de Geus, SN Leslie, TK Lam, W Wang… - Scientific Reports, 2023 - nature.com
Alzheimer's disease (AD) is a complex and heterogeneous neurodegenerative disorder with
contributions from multiple pathophysiological pathways. One of the long-recognized and …

A Proteomic Approach to elucidate the changes in saliva and serum proteins of Pigs with septic and non-septic inflammation

MJ López-Martínez, JJ Cerón, A Ortín-Bustillo… - International journal of …, 2022 - mdpi.com
Sepsis is a systemic inflammatory response triggered by an infectious agent and is
recognized by the World Health Organization as a global concern, since it is one of the …

A manganese-independent aldolase enables Staphylococcus aureus to resist host-imposed metal starvation

PK Párraga Solórzano, TS Bastille, JN Radin… - Mbio, 2023 - Am Soc Microbiol
The preferred carbon source of Staphylococcus aureus and many other pathogens is
glucose, and its consumption is critical during infection. However, glucose utilization …

Is there a difference in the proteomic profile of stimulated and unstimulated saliva samples from pregnant women with/without obesity and periodontitis?

GA Foratori-Junior, TMO Ventura, LT Grizzo… - Cells, 2023 - mdpi.com
This study aimed to compare the proteomic profile of stimulated and unstimulated saliva
samples from pregnant women with/without obesity and periodontitis. Pregnant women were …

The function of lactate dehydrogenase A in retinal neurons: implications to retinal degenerative diseases

A Rajala, MA Bhat, K Teel, GK Gopinadhan Nair… - PNAS …, 2023 - academic.oup.com
The postmitotic retina is highly metabolic and the photoreceptors depend on aerobic
glycolysis for an energy source and cellular anabolic activities. Lactate dehydrogenase A …

Fish Allergy: A Review of Clinical Characteristics, Mechanism, Allergens, Epitopes, and Cross-Reactivity

Y Sun, Y Luo, J Chen, X Liu, J Gao, Y Xie… - ACS Food Science & …, 2024 - ACS Publications
Fish is one of eight foods that can cause severe allergic reactions. The growing consumption
of fish and fish derivatives contributes to an increase in the incidence of fish allergies …

Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases

M Sharma, A Kaur, NM Soler, JP Lingford, R Epa… - Journal of Biological …, 2023 - ASBMB
Sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose) is a sulfosugar that is the anionic head group
of plant, algal, and cyanobacterial sulfolipids: sulfoquinovosyl diacylglycerols. SQ is …