Nucleic acids and their analogues for biomedical applications
F Wang, P Li, HC Chu, PK Lo - Biosensors, 2022 - mdpi.com
Nucleic acids are emerging as powerful and functional biomaterials due to their molecular
recognition ability, programmability, and ease of synthesis and chemical modification …
recognition ability, programmability, and ease of synthesis and chemical modification …
Clinical advances of RNA therapeutics for treatment of neurological and neuromuscular diseases
A Holm, SN Hansen, H Klitgaard, S Kauppinen - RNA biology, 2022 - Taylor & Francis
ABSTRACT RNA therapeutics comprise a diverse group of oligonucleotide-based drugs
such as antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and short …
such as antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and short …
Getting drugs to the brain: advances and prospects of organic nanoparticle delivery systems for assisting drugs to cross the blood–brain barrier
Q Tan, S Zhao, T Xu, Q Wang, M Lan, L Yan… - Journal of materials …, 2022 - pubs.rsc.org
The blood–brain barrier (BBB) plays an irreplaceable role in protecting the central nervous
system (CNS) from bloodborne pathogens. However, the BBB complicates the treatment of …
system (CNS) from bloodborne pathogens. However, the BBB complicates the treatment of …
New drug delivery systems developed for brain targeting
The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSF) are two of
the most complex and sophisticated concierges that defend the central nervous system …
the most complex and sophisticated concierges that defend the central nervous system …
An up-to-date review of natural nanoparticles for cancer management
Cancer represents one of the leading causes of morbidity and mortality worldwide, imposing
an urgent need to develop more efficient treatment alternatives. In this respect, much …
an urgent need to develop more efficient treatment alternatives. In this respect, much …
A stable DNA Tetrahedra–AuNCs nanohybrid: On-site programmed disassembly for tumor imaging and combination therapy
H Sun, T Wang, W Ma, J Huang, B Chen, H Cheng… - Biomaterials, 2022 - Elsevier
Despite DNA nanotechnology has spawned a broad variety and taken a giant leap toward
cancer theranostic applications over the last decade, the homogeneous DNA nanostructures …
cancer theranostic applications over the last decade, the homogeneous DNA nanostructures …
The applications of functionalized DNA nanostructures in bioimaging and cancer therapy
Deoxyribonucleic acid (DNA) is a molecular carrier of genetic information that can be
fabricated into functional nanomaterials in biochemistry and engineering fields. Those DNA …
fabricated into functional nanomaterials in biochemistry and engineering fields. Those DNA …
Nucleic acid nanostructures for in vivo applications: The influence of morphology on biological fate
The development of programmable biomaterials for use in nanofabrication represents a
major advance for the future of biomedicine and diagnostics. Recent advances in structural …
major advance for the future of biomedicine and diagnostics. Recent advances in structural …
“Targeting design” of nanoparticles in tumor therapy
T Yang, J Zhai, D Hu, R Yang, G Wang, Y Li, G Liang - Pharmaceutics, 2022 - mdpi.com
Tumor-targeted therapy based on nanoparticles is a popular research direction in the
biomedical field. After decades of research and development, both the passive targeting …
biomedical field. After decades of research and development, both the passive targeting …
[HTML][HTML] Trends in Nanotechnology to improve therapeutic efficacy across special structures
Cancer is among the leading causes of death worldwide. Its treatment has become a
horrible dream for researchers. Although different approaches have been used to treat …
horrible dream for researchers. Although different approaches have been used to treat …