Leucocyte recruitment is a critical component of the immune response and is central to our
ability to fight infection. Paradoxically, leucocyte recruitment is also a central component of …

Afferent lymphatic vessels (LVs) mediate the transport of antigen and leukocytes to draining
lymph nodes (dLNs), thereby serving as immunologic communication highways between …

With the increasingly early stage lung squamous cell carcinoma (LUSC) being discovered,
there is an urgent need for a comprehensive analysis of the prognostic characteristics of …

Lipedema is an adipofascial disorder that almost exclusively affects women. Lipedema
leads to chronic pain, swelling, and other discomforts due to the bilateral and asymmetrical …

The tumor microenvironment (TME) is an intricate complex and dynamic structure composed
of various cell types, including tumor, stromal and immune cells. Within this complex …

The lymphatic system plays crucial roles in immunity far beyond those of simply providing
conduits for leukocytes and antigens in lymph fluid. Endothelial cells within this vasculature …

A surge of recent studies have identified B cells as pivotal contributors to shaping the tumor
microenvironment (TME) within solid tumors. B cells can both directly and indirectly …

Migrating cells preferentially breach and integrate epithelial and endothelial monolayers at
multicellular vertices. These sites are amenable to forces produced by the migrating cell and …

Throughout our lifetime, each beat of the heart requires the coordinated action of multiple
cardiac cell types. Understanding cardiac cell biology, its intricate microenvironments, and …

The heparan sulfate proteoglycans (HSPGs) are glycoproteins that consist of a proteoglycan
“core” protein and covalently attached heparan sulfate (HS) chain. HSPGs are ubiquitously …