Cytokine imbalance in schizophrenia. from research to clinic: potential implications for treatment

M Reale, E Costantini, NH Greig - Frontiers in psychiatry, 2021 - frontiersin.org
Cytokines are one of the most important components of the immune system. They
orchestrate the brain's response to infectious and other exogenous insults and are crucial …

[HTML][HTML] The role of aberrations in the immune-inflammatory response system (IRS) and the compensatory immune-regulatory reflex system (CIRS) in different …

C Roomruangwong, C Noto, B Kanchanatawan… - Molecular …, 2020 - Springer
Several lines of evidence indicate that aberrations in immune-inflammatory pathways may
contribute to the pathophysiology of schizophrenia spectrum disorders. Here, we propose a …

[HTML][HTML] IL-3 in the development and function of basophils

G Varricchi, R Poto, G Marone, JT Schroeder - Seminars in immunology, 2021 - Elsevier
The β common chain (βc) cytokine family includes granulocyte-macrophage colony-
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …

[HTML][HTML] The Interrelationships between Cytokines and Schizophrenia: A Systematic Review

H Lv, M Guo, C Guo, K He - International Journal of Molecular Sciences, 2024 - mdpi.com
Schizophrenia (SCZ) imposes a significant burden on patients and their families because of
its high prevalence rate and disabling nature. Given the lack of definitive conclusions …

[HTML][HTML] LILRB4, from the immune system to the disease target

J Liu, Q Wu, J Shi, W Guo, X Jiang… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Leukocyte immunoglobulin (Ig)-like receptor B4 (LILRB4) is a member of leukocyte Ig-like
receptors (LILRs), which associate with membrane adaptors to signal through multiple …

Role of the β Common (βc) Family of Cytokines in Health and Disease

TR Hercus, WLT Kan, SE Broughton… - Cold Spring …, 2018 - cshperspectives.cshlp.org
The β common ([βc]/CD131) family of cytokines comprises granulocyte macrophage colony-
stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5, all of which use βc as their key …

Altered serum tumor necrosis factor and interleukin-1β in first-episode drug-naive and chronic schizophrenia

F Zhu, L Zhang, F Liu, R Wu, W Guo, J Ou… - Frontiers in …, 2018 - frontiersin.org
Objective: Abnormality of the immune system might play a significant role in the
pathogenesis of schizophrenia. We want to identity whether the serum TNF-α and IL-1β …

Interleukin-17 alteration in first-episode psychosis: a meta-analysis

X Fang, Y Zhang, W Fan, W Tang, C Zhang - Complex Psychiatry, 2018 - karger.com
Schizophrenia is accompanied with central nervous system and peripheral immune system
imbalances. Interleukin-17 (IL-17) is implicated in various immune and inflammatory …

The role of aberrations in the immune-inflammatory reflex system (IRS) and the compensatory immune-regulatory reflex system (CIRS) in different phenotypes of …

C Roomruangwong, C Noto, B Kanchanatawan… - 2018 - preprints.org
In this paper we propose a novel theoretical framework, which was previously developed for
major depression and bipolar disorder, namely the compensatory immune-regulatory reflex …

The role of cytokines in schizophrenia

I Binić, J Petrović, J Antonijević, D Pančić… - Acta Medica …, 2023 - aseestant.ceon.rs
Sažetak Shizofrenija, multisistemski poremećaj sa nejasnom etiologijom, povezana je i sa
imunološkom disfunkcijom, uključujući i izmenjene nivoe citokina. Potencijalna uloga …